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Tuesday, December 30, 2025 10:27 PM

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CSIR, ICMR Chart Joint Roadmap to Boost Collaborative Health Research

The Council of Scientific and Industrial Research (CSIR) and the Indian Council of Medical Research (ICMR) held a high-level strategy meeting to advance a unified roadmap for collaborative health research, the Ministry of Science & Technology said on Tuesday. The session took place at the CSIR Science Centre in New Delhi and was co-chaired by N. Kalaiselvi, Director General of CSIR, and Rajiv Bahl, Director General of ICMR and Secretary, Department of Health Research. The two organisations reviewed progress on major joint initiatives, including CSIR-developed molecules progressing toward clinical trials, updates on ICMR-supported Centres of Advanced Research within CSIR labs, and implementation of large-scale national projects. The meeting also emphasised expanding wastewater surveillance for a wider range of pathogens across cities, hospitals and communities, aligning with the One Health Mission. Discussions included defining the roles of CSIR and ICMR in drug development, clinical trials, and leveraging ICMR’s large-animal toxicity testing infrastructure. The joint AcSIR–ICMR Ph.D. programme was also reviewed, with a focus on widening opportunities for young researchers by integrating ICMR and CSIR fellowship pathways. Both Dr. Kalaiselvi and Dr. Bahl stressed the importance of combining CSIR’s scientific and technological expertise with ICMR’s public health capabilities to deliver national-scale outcomes. They highlighted the need for structured, time-bound collaboration, particularly for co-developing technologies such as a digitally operated medical emergency drone service. Experts concluded by reaffirming plans to deepen cooperation in biomedical sciences, diagnostics, digital health, environmental surveillance, and other emerging healthcare domains. Source: IANS

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New Study: 45% of Heart Attack Risks Go Undetected by Current Screening Methods

A new study has revealed that widely used cardiac screening methods may be overlooking 45% of individuals who are genuinely at risk of a heart attack. The research, conducted by experts at the Mount Sinai, highlights a significant gap in current patient assessment practices, showing that depending solely on standard risk scores and symptoms may leave many vulnerable. The findings, published in JACC: Advances, point to the dangers of silent plaque buildup in arteries—often undetected until it becomes life-threatening. Lead author Amir Ahmadi said population-based risk tools fail to capture true individual risk. He noted that if patients were assessed just two days before their heart attack, nearly half would not have qualified for further testing or preventive treatment under current guidelines. Researchers evaluated two major tools—the traditional ASCVD risk score and a newer, more detailed model called PREVENT calculator—using data from 474 patients under age 66 with no known coronary artery disease. They found that: ASCVD would have classified almost 50% of patients as low or borderline risk. PREVENT would have misclassified more than 60% of them. Additionally, 60% of patients reported no symptoms—such as chest discomfort or breathlessness—until less than two days before their heart attack, making symptom-based screening unreliable. The study suggests shifting from symptom- and score-based evaluation to atherosclerosis imaging, which can detect silent plaque early and potentially prevent heart attacks before they occur. Source: IANS

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Thyrocare rolls out GLP-1 Health Check packages to support safe use of weight-loss and diabetes drugs

Thyrocare Technologies Ltd. has introduced a new set of diagnostic packages called the GLP-1 Health Check, designed to help individuals using GLP-1–based medications for weight management and type 2 diabetes track their overall health. The nationwide offering includes up to 81 tests, starting at ₹2,799, aimed at monitoring key metabolic, nutritional, liver, kidney and thyroid markers both before beginning GLP-1 therapy and during ongoing treatment. GLP-1 agonists—drugs that replicate the action of the hormone glucagon-like peptide-1—have rapidly grown in demand for obesity and diabetes management. With their rising use, doctors have stressed the need for continuous health monitoring to ensure treatment efficacy and early detection of adverse reactions. According to Thyrocare, the panels were developed with guidance from leading clinicians to help users establish baseline health data, identify possible nutrient deficiencies and track metabolic changes. The test menu includes lipid profile, fasting glucose, fasting insulin, HOMA-IR, liver and kidney function tests, and cardiac risk markers. Kidney assessments have been emphasized as GLP-1 medicines may cause dehydration or electrolyte disturbances. Since these therapies can suppress appetite and contribute to vitamin deficiencies, the packages also check vitamin D, vitamin B12 and hemoglobin levels. Tests for amylase and lipase help screen for pancreatitis, while thyroid markers (T3, T4, TSH) monitor potential therapy-related hormonal shifts. Thyrocare said that offering all these tests in one bundle simplifies comprehensive monitoring for people on GLP-1 medications. Rahul Guha, managing director and CEO of Thyrocare, said the growing adoption of GLP-1 drugs in India calls for reliable diagnostic support. “These therapies are powerful and effective when used responsibly, and consistent monitoring ensures better outcomes,” he noted. Endocrinologist Dr. Shehla Shaikh added that structured medical oversight is crucial for safe weight-management treatment. Comprehensive testing, she said, helps safeguard nutritional balance, organ function and long-term safety. The GLP-1 Health Check packages can be booked through Thyrocare, PharmEasy, and partner platforms, aligning with Thyrocare’s broader push toward preventive and precision healthcare for metabolic and lifestyle-related conditions. Source: Economic Times

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AI Tool Boosts India’s Disease Surveillance, Generates Over 5,000 Alerts: Study

An artificial intelligence–powered surveillance system deployed by the National Centre for Disease Control (NCDC) has significantly strengthened India’s ability to track infectious disease outbreaks, generating more than 5,000 real-time alerts for health authorities since 2022, according to a new pre-print study. Developed by WadhwaniAI, the Health Sentinel platform has automated the labor-intensive task of scanning news reports for unusual health events. The system reportedly reduced manual workload by 98%, enabling faster outbreak detection and quicker public health action. The findings are currently under review and not yet peer-reviewed. Under India’s Integrated Disease Surveillance Programme (IDSP), media scanning and verification has long relied on manual review of print, television and online news. Health Sentinel upgrades this process by screening articles daily across 13 languages, applying AI models to highlight potential threats that are later reviewed by epidemiologists. According to the study, the platform has processed over 300 million news articles since April 2022, identifying 95,000+ unique health-related events, of which around 3,500 were shortlisted by NCDC experts as possible outbreaks. Researchers also estimate that the AI-enabled system triggered more than 5,000 actionable alerts between April 2022 and April 2025. Parag Govil, National Program Lead for Global Health Security at WadhwaniAI, said the tool preserves human oversight while eliminating the time-consuming manual scanning traditionally required. Epidemiologists validate flagged events before disseminating them to state and district authorities. The research team noted a 150% surge in published health events captured since adopting AI-assisted surveillance, compared to earlier years of fully manual analysis. In 2024 alone, 96% of reported events were identified through the AI system, with only 4% coming from manual review. Globally, event-based surveillance techniques that incorporate online media or social media sources are increasingly used to complement traditional “passive reporting” from healthcare providers. The volume of daily online content, however, has made manual screening impractical, making automated systems essential. The article also references other Indian studies highlighting the value of enhanced surveillance. A pilot conducted in six private hospitals in Kasaragod, Kerala, used an algorithm to analyse cases of acute febrile illness (AFI). The system detected 88 clusters, with several verified as outbreaks—including dengue and COVID-19—demonstrating the benefits of early, data-driven detection. International research supports similar conclusions. A 2020 review in the Journal of Biomedical Informatics found that machine learning–based analysis of social media posts, especially on Twitter, improved disease trend prediction. Another study, published in 2017 in the American Journal of Tropical Medicine and Hygiene, showed that mining news articles can help fill gaps when official national case data is delayed. Overall, the findings underscore the growing importance of AI-driven surveillance systems in strengthening public health response capabilities and improving global health security. Source: PTI

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Study Links Chronic Fatigue Syndrome to Abnormal Breathing Patterns

A new study has revealed that individuals suffering from chronic fatigue syndrome (CFS) may often experience abnormal breathing patterns, offering fresh insight into potential treatment strategies for managing the condition. Researchers from the Icahn School of Medicine at Mount Sinai in the United States monitored 57 patients diagnosed with CFS during physical activity to better understand the link between fatigue and respiratory function. The findings, published in the journal Frontiers in Medicine, showed that many patients exhibited dysfunctional breathing—ranging from deep sighs during normal breathing to overly rapid or shallow breaths that prevent the lungs from fully expanding. Chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME/CFS), is characterized by extreme tiredness that does not improve with rest, along with cognitive issues such as brain fog and concentration difficulties. The researchers observed that a lack of coordination between the chest and abdominal muscles can further disrupt normal breathing mechanics. Lead author Dr. Donna Mancini explained, “Patients can have dysfunctional breathing without realizing it, and it can occur even when they are at rest. While the symptoms of hyperventilation are well understood, we still need to explore how dysfunctional breathing specifically affects ME/CFS patients.” The study compared the heart rate, blood pressure, and oxygen saturation of the 57 ME/CFS patients with those of 25 healthy participants during cardiopulmonary exercises over two days. Despite taking in similar amounts of oxygen, around 71% of the patients displayed breathing irregularities, including hyperventilation, dysfunctional breathing, or both. The researchers noted that such breathing issues can mimic or worsen symptoms commonly seen in chronic fatigue, including dizziness, breathlessness, chest pain, anxiety, and difficulty focusing. In fact, nine participants were found to experience both hyperventilation and dysfunctional breathing simultaneously. The study also suggests that these respiratory abnormalities might aggravate post-exertional malaise—a hallmark symptom of ME/CFS in which patients’ fatigue and discomfort intensify after physical or mental exertion. Identifying and addressing dysfunctional breathing, the authors said, could open new avenues for therapy and symptom management in chronic fatigue patients. Source: PTI

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DGCA proposes full airfare refund for passengers cancelling flights due to medical emergencies

The Directorate General of Civil Aviation (DGCA) has issued draft guidelines introducing new norms for airline ticket refunds and facilities for differently abled passengers. Under the proposed regulations, passengers who cancel their flight due to a medical emergency will be eligible for a full refund or a credit note, marking a significant consumer-friendly reform in air travel policies. The aviation regulator has also clarified that airlines will bear direct responsibility for processing refunds, even for tickets booked through travel agents or online portals, since these intermediaries act as the airline’s representatives. Refunds must be completed within 21 working days, as per the draft titled “Refund of Airline Tickets to Passengers of Public Transport Undertakings.” Public feedback on these proposals is open until November 30, 2025. In another passenger-friendly change, the DGCA has suggested extending the free ticket amendment window from 24 hours to 48 hours, provided the modification is made at least five days before a domestic flight or 15 days before an international flight. This replaces the earlier seven-day uniform rule for all routes. Separately, the DGCA has finalized updated norms to improve the air travel experience for differently abled passengers. Airlines may now charge able-bodied passengers who request wheelchair assistance, ensuring the limited supply remains available to those who genuinely need it. Airports will also face stricter obligations — they must provide ambulifts for passengers using wheelchairs and, where unavailable, towable ramps or stepladders as alternatives. Disability rights advocates, however, have criticized the latter provision as a step backward. Furthermore, airports are required to ensure clear signage, designated cab drop-off zones, and adequate staff to assist differently abled travellers. They are also encouraged to introduce digital navigation maps to enhance accessibility and independence for such passengers. Source: The Hindu

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ICMR Study Finds 1 in 9 People Tested Positive for Infectious Diseases in 2025

A recent nationwide analysis by the Indian Council of Medical Research (ICMR) has revealed that 11.1% of patients tested across India were found carrying infectious pathogens — roughly one in every nine individuals tested. The large-scale study, conducted through ICMR’s Virus Research and Diagnostic Laboratories (VRDL) network, aimed to track viral infections of public health concern. The five most commonly detected pathogens included Influenza A in acute respiratory infections (ARI/SARI), Dengue virus in cases of acute and haemorrhagic fever, Hepatitis A among jaundice patients, Norovirus in acute diarrhoeal disease (ADD) outbreaks, and Herpes Simplex Virus (HSV) in acute encephalitis syndrome (AES) cases. The ICMR report noted a rise in infection rates from 10.7% in the first quarter (January–March) to 11.5% in the second quarter (April–June) of 2025. Out of 2,28,856 samples tested in the first quarter, 24,502 showed the presence of pathogens, while 26,055 of 2,26,095 samples tested positive in the next quarter — marking an increase of 0.8 percentage points. A senior ICMR scientist cautioned that although the increase appears modest, it could be an early signal for seasonal outbreaks or emerging infections, underscoring the importance of continued surveillance. “Even small shifts in infection rates can serve as an early warning for potential epidemics. The VRDL network plays a vital role as India’s early detection system,” the scientist said. Between April and June 2025, 191 disease clusters were investigated, identifying infections such as mumps, measles, rubella, dengue, chikungunya, rotavirus, norovirus, varicella zoster virus, Epstein-Barr virus (EBV), and astrovirus. In comparison, 389 clusters were probed between January and March 2025, detecting a similar range of pathogens including hepatitis, influenza, Leptospira, and sexually transmitted infections (STIs). From 2014 to 2024, the VRDL network tested over 40 lakh samples, identifying pathogens in 18.8% of them. The network has seen rapid expansion — from 27 laboratories in 2014 to 165 labs across 31 states and Union Territories by 2025 — and has so far tracked 2,534 disease clusters nationwide. Source: PTI Photo Credit: Getty Images/iStockphoto

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Supreme Court Directs NHRC to Oversee Mental Health Authorities Nationwide

In a significant move to strengthen mental healthcare governance, the Supreme Court on Tuesday (October 28, 2025) directed the National Human Rights Commission (NHRC) to monitor the functioning of Central and State Mental Health Authorities across India. The decision, issued by a Bench led by Justice P.S. Narasimha, came in response to a 2018 petition filed by advocate Gaurav Kumar Bansal, which exposed the inhumane treatment of mentally ill inmates who were found chained in a faith-based asylum in Badayun, Uttar Pradesh. The petition had called for the establishment and independent monitoring of Central and State Mental Health Authorities, along with dedicated funding and mental health review boards, as mandated under the Mental Healthcare Act, 2017. Following the petition, the Union Health Ministry informed the Court through an affidavit that these authorities had been formally notified and were operational. Acknowledging this development, the Bench observed: “Since both the Central and State Mental Health Authorities are now functioning, the NHRC shall oversee the matter, hear the concerned bodies, and issue necessary directions to ensure their effective working.” The Supreme Court further instructed that the petition be treated as a “complaint” by the NHRC and monitored accordingly under existing legal provisions. The NHRC has been empowered to issue appropriate orders to ensure that mental health institutions and review boards function efficiently and uphold human rights standards. This directive marks an important step toward ensuring accountability and systemic reform within India’s mental healthcare framework. Source: The Hindu  

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CPCB detects heavy metals in air across Delhi and nine other Indian cities

The Central Pollution Control Board (CPCB) has informed the National Green Tribunal (NGT) that heavy metals such as copper, zinc, chromium, and molybdenum have been detected in the air of ten Indian cities, including Delhi, where they constitute between 0.1% and 2.1% of the total PM10 concentration. The other cities included in the study are Jaipur, Bhopal, Lucknow, Ahmedabad, Nagpur, Kolkata, Bengaluru, Visakhapatnam, and Chennai. For Delhi, the CPCB collected air samples from Pitampura, Siri Fort, Janakpuri, and Shahdara during June and July 2025. The analysis followed an NGT directive from last year, which took suo motu cognisance of a Times of India report highlighting the presence of heavy metals in PM2.5 particles in East Delhi’s air. According to CPCB’s findings, these metals are typically bound to airborne particulate matter, meaning that reducing PM concentrations would likely lower their levels as well. During the monitoring period, Delhi’s average PM10 concentration was recorded at 130 µg/m³, with copper at 55.13 ng/m³, chromium at 12.25 ng/m³, molybdenum at 0.91 ng/m³, and zinc at 243.5 ng/m³. Previous studies have shown that chromium, copper, zinc, molybdenum, and lead are among the most common heavy metals present in PM2.5 in Delhi and other cities. The Heavy Metal Exposure Index (HEI) developed by researchers showed that East Delhi had one of the highest toxicity loads before the COVID-19 lockdown, later surpassed by Ludhiana. Areas such as Mayur Vihar, Dilshad Garden, and Laxmi Nagar were found to have significant levels. Lead researcher Kanhaiya Lal noted that India lacks national ambient air quality standards for several heavy metals, unlike countries such as Canada, which have established benchmarks. He also warned that airborne heavy metals pose serious health risks due to their toxic nature. The CPCB reiterated that under the National Clean Air Programme (NCAP) — launched in 2019 by the Ministry of Environment, Forest and Climate Change — India aims to achieve up to a 40% reduction in PM10 levels or meet the national standard of 60 µg/m³ by 2025–26, using 2017–18 as the baseline year. Source: TNN

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Scientists Explore How Music Can Help Relieve Pain from Surgery and Illness

In the recovery ward at UC San Diego Health, nurse Rod Salaysay relies on more than just medical tools like a stethoscope or thermometer — he also uses his guitar and ukulele. Between post-surgery medications, Salaysay plays tunes at patients’ request, ranging from folk songs and classical pieces like Minuet in G Major to movie classics such as Somewhere Over the Rainbow. The results are often visible: patients smile, relax, and sometimes even require fewer painkillers. “In hospitals, pain, anxiety, and worry often feed into each other,” Salaysay explained. “Music can help break that cycle.” Over the last twenty years, hospitals and clinics worldwide have increasingly turned to music therapy — both live and recorded — as studies continue to reveal its power to ease physical and emotional pain. While music’s emotional influence has long been understood, scientists are only now uncovering how music-induced analgesia — the process by which music reduces pain perception — actually works. Although a melody can’t replace strong pain medication, research published in Pain and Scientific Reports shows that listening to music can lessen pain intensity and increase a person’s tolerance to discomfort. What seems crucial, researchers say, is that patients choose the music themselves and listen attentively, rather than passively. “Pain is incredibly complex,” said Adam Hanley, a psychologist at Florida State University. “It’s shaped by both the body’s sensations and our emotional and mental responses to those sensations.” Even with the same condition, two people might experience pain differently. Acute pain comes from immediate physical triggers, while chronic pain involves long-term changes in the brain that heighten sensitivity. “Pain is processed and interpreted by the brain,” said Dr. Gilbert Chandler, a chronic spinal pain expert from Tallahassee Orthopedic Clinic, “and the brain can amplify or reduce those signals.” Music, experts note, helps redirect attention away from pain. Studies suggest that preferred music is especially effective, even more than podcasts or generic playlists. “Music doesn’t just distract — it engages the whole brain,” said Caroline Palmer, a psychologist at McGill University. “That’s why it changes how people experience pain.” Indeed, Kate Richards Geller, a Los Angeles-based music therapist, explains that engaging with music activates nearly every brain region, easing not just pain but also isolation and anxiety. The use of music for pain relief dates back to the 19th century, when patients listened to melodies during dental procedures before anesthetics were common. Modern researchers continue to explore what makes it most effective. In one experiment at Erasmus University Rotterdam, scientists tested 548 participants across five music genres — classical, rock, pop, urban, and electronic — to measure how long they could withstand cold-induced pain. All genres helped, but none outperformed the others. “The best music is simply what you like,” said study co-author Dr. Emy van der Valk Bouman, noting that familiar songs may trigger memories and emotions that enhance resilience. Allowing patients to choose their music can also restore a sense of control and agency, said Claire Howlin of Trinity College Dublin, whose research shows that self-selected songs can boost pain tolerance. Hanley’s studies further indicate that focused, daily listening may gradually reduce chronic pain, offering an uplifting “emotional bump” without side effects. For many, it’s a powerful, drug-free remedy. Cecily Gardner, a jazz vocalist from California, said music helped her cope with illness and brought comfort to others in pain. “Music reduces stress, connects people,” she said, “and transports you somewhere better.” Source: AP

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