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Study Links Chronic Fatigue Syndrome to Abnormal Breathing Patterns

A new study has revealed that individuals suffering from chronic fatigue syndrome (CFS) may often experience abnormal breathing patterns, offering fresh insight into potential treatment strategies for managing the condition. Researchers from the Icahn School of Medicine at Mount Sinai in the United States monitored 57 patients diagnosed with CFS during physical activity to better understand the link between fatigue and respiratory function. The findings, published in the journal Frontiers in Medicine, showed that many patients exhibited dysfunctional breathing—ranging from deep sighs during normal breathing to overly rapid or shallow breaths that prevent the lungs from fully expanding. Chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME/CFS), is characterized by extreme tiredness that does not improve with rest, along with cognitive issues such as brain fog and concentration difficulties. The researchers observed that a lack of coordination between the chest and abdominal muscles can further disrupt normal breathing mechanics. Lead author Dr. Donna Mancini explained, “Patients can have dysfunctional breathing without realizing it, and it can occur even when they are at rest. While the symptoms of hyperventilation are well understood, we still need to explore how dysfunctional breathing specifically affects ME/CFS patients.” The study compared the heart rate, blood pressure, and oxygen saturation of the 57 ME/CFS patients with those of 25 healthy participants during cardiopulmonary exercises over two days. Despite taking in similar amounts of oxygen, around 71% of the patients displayed breathing irregularities, including hyperventilation, dysfunctional breathing, or both. The researchers noted that such breathing issues can mimic or worsen symptoms commonly seen in chronic fatigue, including dizziness, breathlessness, chest pain, anxiety, and difficulty focusing. In fact, nine participants were found to experience both hyperventilation and dysfunctional breathing simultaneously. The study also suggests that these respiratory abnormalities might aggravate post-exertional malaise—a hallmark symptom of ME/CFS in which patients’ fatigue and discomfort intensify after physical or mental exertion. Identifying and addressing dysfunctional breathing, the authors said, could open new avenues for therapy and symptom management in chronic fatigue patients. Source: PTI

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DGCA proposes full airfare refund for passengers cancelling flights due to medical emergencies

The Directorate General of Civil Aviation (DGCA) has issued draft guidelines introducing new norms for airline ticket refunds and facilities for differently abled passengers. Under the proposed regulations, passengers who cancel their flight due to a medical emergency will be eligible for a full refund or a credit note, marking a significant consumer-friendly reform in air travel policies. The aviation regulator has also clarified that airlines will bear direct responsibility for processing refunds, even for tickets booked through travel agents or online portals, since these intermediaries act as the airline’s representatives. Refunds must be completed within 21 working days, as per the draft titled “Refund of Airline Tickets to Passengers of Public Transport Undertakings.” Public feedback on these proposals is open until November 30, 2025. In another passenger-friendly change, the DGCA has suggested extending the free ticket amendment window from 24 hours to 48 hours, provided the modification is made at least five days before a domestic flight or 15 days before an international flight. This replaces the earlier seven-day uniform rule for all routes. Separately, the DGCA has finalized updated norms to improve the air travel experience for differently abled passengers. Airlines may now charge able-bodied passengers who request wheelchair assistance, ensuring the limited supply remains available to those who genuinely need it. Airports will also face stricter obligations — they must provide ambulifts for passengers using wheelchairs and, where unavailable, towable ramps or stepladders as alternatives. Disability rights advocates, however, have criticized the latter provision as a step backward. Furthermore, airports are required to ensure clear signage, designated cab drop-off zones, and adequate staff to assist differently abled travellers. They are also encouraged to introduce digital navigation maps to enhance accessibility and independence for such passengers. Source: The Hindu

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ICMR Study Finds 1 in 9 People Tested Positive for Infectious Diseases in 2025

A recent nationwide analysis by the Indian Council of Medical Research (ICMR) has revealed that 11.1% of patients tested across India were found carrying infectious pathogens — roughly one in every nine individuals tested. The large-scale study, conducted through ICMR’s Virus Research and Diagnostic Laboratories (VRDL) network, aimed to track viral infections of public health concern. The five most commonly detected pathogens included Influenza A in acute respiratory infections (ARI/SARI), Dengue virus in cases of acute and haemorrhagic fever, Hepatitis A among jaundice patients, Norovirus in acute diarrhoeal disease (ADD) outbreaks, and Herpes Simplex Virus (HSV) in acute encephalitis syndrome (AES) cases. The ICMR report noted a rise in infection rates from 10.7% in the first quarter (January–March) to 11.5% in the second quarter (April–June) of 2025. Out of 2,28,856 samples tested in the first quarter, 24,502 showed the presence of pathogens, while 26,055 of 2,26,095 samples tested positive in the next quarter — marking an increase of 0.8 percentage points. A senior ICMR scientist cautioned that although the increase appears modest, it could be an early signal for seasonal outbreaks or emerging infections, underscoring the importance of continued surveillance. “Even small shifts in infection rates can serve as an early warning for potential epidemics. The VRDL network plays a vital role as India’s early detection system,” the scientist said. Between April and June 2025, 191 disease clusters were investigated, identifying infections such as mumps, measles, rubella, dengue, chikungunya, rotavirus, norovirus, varicella zoster virus, Epstein-Barr virus (EBV), and astrovirus. In comparison, 389 clusters were probed between January and March 2025, detecting a similar range of pathogens including hepatitis, influenza, Leptospira, and sexually transmitted infections (STIs). From 2014 to 2024, the VRDL network tested over 40 lakh samples, identifying pathogens in 18.8% of them. The network has seen rapid expansion — from 27 laboratories in 2014 to 165 labs across 31 states and Union Territories by 2025 — and has so far tracked 2,534 disease clusters nationwide. Source: PTI Photo Credit: Getty Images/iStockphoto

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Supreme Court Directs NHRC to Oversee Mental Health Authorities Nationwide

In a significant move to strengthen mental healthcare governance, the Supreme Court on Tuesday (October 28, 2025) directed the National Human Rights Commission (NHRC) to monitor the functioning of Central and State Mental Health Authorities across India. The decision, issued by a Bench led by Justice P.S. Narasimha, came in response to a 2018 petition filed by advocate Gaurav Kumar Bansal, which exposed the inhumane treatment of mentally ill inmates who were found chained in a faith-based asylum in Badayun, Uttar Pradesh. The petition had called for the establishment and independent monitoring of Central and State Mental Health Authorities, along with dedicated funding and mental health review boards, as mandated under the Mental Healthcare Act, 2017. Following the petition, the Union Health Ministry informed the Court through an affidavit that these authorities had been formally notified and were operational. Acknowledging this development, the Bench observed: “Since both the Central and State Mental Health Authorities are now functioning, the NHRC shall oversee the matter, hear the concerned bodies, and issue necessary directions to ensure their effective working.” The Supreme Court further instructed that the petition be treated as a “complaint” by the NHRC and monitored accordingly under existing legal provisions. The NHRC has been empowered to issue appropriate orders to ensure that mental health institutions and review boards function efficiently and uphold human rights standards. This directive marks an important step toward ensuring accountability and systemic reform within India’s mental healthcare framework. Source: The Hindu  

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CPCB detects heavy metals in air across Delhi and nine other Indian cities

The Central Pollution Control Board (CPCB) has informed the National Green Tribunal (NGT) that heavy metals such as copper, zinc, chromium, and molybdenum have been detected in the air of ten Indian cities, including Delhi, where they constitute between 0.1% and 2.1% of the total PM10 concentration. The other cities included in the study are Jaipur, Bhopal, Lucknow, Ahmedabad, Nagpur, Kolkata, Bengaluru, Visakhapatnam, and Chennai. For Delhi, the CPCB collected air samples from Pitampura, Siri Fort, Janakpuri, and Shahdara during June and July 2025. The analysis followed an NGT directive from last year, which took suo motu cognisance of a Times of India report highlighting the presence of heavy metals in PM2.5 particles in East Delhi’s air. According to CPCB’s findings, these metals are typically bound to airborne particulate matter, meaning that reducing PM concentrations would likely lower their levels as well. During the monitoring period, Delhi’s average PM10 concentration was recorded at 130 µg/m³, with copper at 55.13 ng/m³, chromium at 12.25 ng/m³, molybdenum at 0.91 ng/m³, and zinc at 243.5 ng/m³. Previous studies have shown that chromium, copper, zinc, molybdenum, and lead are among the most common heavy metals present in PM2.5 in Delhi and other cities. The Heavy Metal Exposure Index (HEI) developed by researchers showed that East Delhi had one of the highest toxicity loads before the COVID-19 lockdown, later surpassed by Ludhiana. Areas such as Mayur Vihar, Dilshad Garden, and Laxmi Nagar were found to have significant levels. Lead researcher Kanhaiya Lal noted that India lacks national ambient air quality standards for several heavy metals, unlike countries such as Canada, which have established benchmarks. He also warned that airborne heavy metals pose serious health risks due to their toxic nature. The CPCB reiterated that under the National Clean Air Programme (NCAP) — launched in 2019 by the Ministry of Environment, Forest and Climate Change — India aims to achieve up to a 40% reduction in PM10 levels or meet the national standard of 60 µg/m³ by 2025–26, using 2017–18 as the baseline year. Source: TNN

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Scientists Explore How Music Can Help Relieve Pain from Surgery and Illness

In the recovery ward at UC San Diego Health, nurse Rod Salaysay relies on more than just medical tools like a stethoscope or thermometer — he also uses his guitar and ukulele. Between post-surgery medications, Salaysay plays tunes at patients’ request, ranging from folk songs and classical pieces like Minuet in G Major to movie classics such as Somewhere Over the Rainbow. The results are often visible: patients smile, relax, and sometimes even require fewer painkillers. “In hospitals, pain, anxiety, and worry often feed into each other,” Salaysay explained. “Music can help break that cycle.” Over the last twenty years, hospitals and clinics worldwide have increasingly turned to music therapy — both live and recorded — as studies continue to reveal its power to ease physical and emotional pain. While music’s emotional influence has long been understood, scientists are only now uncovering how music-induced analgesia — the process by which music reduces pain perception — actually works. Although a melody can’t replace strong pain medication, research published in Pain and Scientific Reports shows that listening to music can lessen pain intensity and increase a person’s tolerance to discomfort. What seems crucial, researchers say, is that patients choose the music themselves and listen attentively, rather than passively. “Pain is incredibly complex,” said Adam Hanley, a psychologist at Florida State University. “It’s shaped by both the body’s sensations and our emotional and mental responses to those sensations.” Even with the same condition, two people might experience pain differently. Acute pain comes from immediate physical triggers, while chronic pain involves long-term changes in the brain that heighten sensitivity. “Pain is processed and interpreted by the brain,” said Dr. Gilbert Chandler, a chronic spinal pain expert from Tallahassee Orthopedic Clinic, “and the brain can amplify or reduce those signals.” Music, experts note, helps redirect attention away from pain. Studies suggest that preferred music is especially effective, even more than podcasts or generic playlists. “Music doesn’t just distract — it engages the whole brain,” said Caroline Palmer, a psychologist at McGill University. “That’s why it changes how people experience pain.” Indeed, Kate Richards Geller, a Los Angeles-based music therapist, explains that engaging with music activates nearly every brain region, easing not just pain but also isolation and anxiety. The use of music for pain relief dates back to the 19th century, when patients listened to melodies during dental procedures before anesthetics were common. Modern researchers continue to explore what makes it most effective. In one experiment at Erasmus University Rotterdam, scientists tested 548 participants across five music genres — classical, rock, pop, urban, and electronic — to measure how long they could withstand cold-induced pain. All genres helped, but none outperformed the others. “The best music is simply what you like,” said study co-author Dr. Emy van der Valk Bouman, noting that familiar songs may trigger memories and emotions that enhance resilience. Allowing patients to choose their music can also restore a sense of control and agency, said Claire Howlin of Trinity College Dublin, whose research shows that self-selected songs can boost pain tolerance. Hanley’s studies further indicate that focused, daily listening may gradually reduce chronic pain, offering an uplifting “emotional bump” without side effects. For many, it’s a powerful, drug-free remedy. Cecily Gardner, a jazz vocalist from California, said music helped her cope with illness and brought comfort to others in pain. “Music reduces stress, connects people,” she said, “and transports you somewhere better.” Source: AP

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Bengaluru’s Airbound Partners with Narayana Health to Launch Drone-Based Medical Deliveries

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Bengaluru-based autonomous logistics startup Airbound has joined hands with Narayana Health to pilot medical deliveries using drones, marking a major step toward integrating advanced drone technology into India’s healthcare logistics system. As part of the three-month pilot programme, Airbound will carry out around 10 drone-based deliveries per day, transporting critical medical items such as blood samples, diagnostic test kits, and essential supplies between healthcare facilities. “This collaboration with Narayana Health demonstrates our ability to handle the most demanding delivery needs while showcasing the cost benefits that make our model globally scalable,” said Naman Pushp, Founder and CEO of Airbound. Airbound described the initiative as a “high-stakes proof of concept” designed to validate drone technology’s reliability, efficiency, and cost-effectiveness for critical healthcare applications. Dr. Devi Shetty, Founder and Chairman of Narayana Health, noted, “Our partnership with Airbound enables us to explore a promising technology that can greatly enhance the speed and dependability of medical logistics. This aligns with our mission to harness innovation for improving patient outcomes, especially in situations where rapid access to diagnostics and supplies can be life-saving.” Airbound’s drones are capable of carrying a payload-to-aircraft mass ratio of 1 kg to 1.5 kg. The company highlighted that its blended-wing-body tailsitter design allows vertical takeoff and landing while maintaining the aerodynamic efficiency of fixed-wing flight—addressing the limitations found in traditional tilt-rotor and quadplane configurations. In addition to the partnership, Airbound announced securing $8.65 million in seed funding, led by Lachy Groom (Co-founder, Physical Intelligence), with participation from Humba Ventures, Lightspeed Venture Partners, and senior executives from Tesla, Anduril, and Ather Energy. With this round, Airbound’s total funding has surpassed $10 million. The company plans to use the funds to scale up manufacturing, expand beyond healthcare logistics, refine its drone technology, and prepare for large-scale market deployment by 2026. Insights gained from the Narayana Health pilot will help Airbound enhance its future logistics solutions, cut delivery costs, and accelerate adoption across multiple sectors. Source: The Hindu

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Study Identifies 750 Genes Influencing Human Metabolism Through Blood Molecules

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A large-scale genetic study has identified around 750 genes that may play a key role in human metabolism by regulating levels of approximately 250 different blood molecules, including lipids and amino acids. The research suggests these genetic influences are consistent across ancestries and genders, offering broad implications for understanding metabolic health. The study, led by scientists from the Berlin Institute of Health at Charité–Universitätsmedizin Berlin and Queen Mary University of London, analysed genetic data from nearly 4.5 lakh individuals of European, African, and Asian ancestry in the UK Biobank. Published in Nature Genetics, the findings revealed 29,824 genetic locus–metabolite associations mapped to 753 genomic regions, many of which had not previously been linked to metabolic processes. This discovery expands current knowledge of metabolic pathways and their connection to disease risks. The researchers found that the genetic regulation of blood metabolites showed strong consistency across populations, suggesting the potential for universal metabolic insights. Some of the identified genes, such as VEGFA, were newly linked to cholesterol regulation and may open pathways for novel drug development aimed at preventing heart disease. Lead author Martijn Zoodsma, a postdoctoral researcher at BIH, said the study offers a “systematic map of the genetic control of hundreds of blood molecules,” providing a valuable foundation for understanding disease susceptibility and metabolic diversity. Senior author Prof. Maik Pietzner added that despite advances like statins, heart disease remains a leading cause of death, and these findings could guide the creation of next-generation therapies targeting lipid build-up in arteries. Source: PTI  

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IAP Kerala Urges Caution: Avoid Self-Medication and Follow Rational Prescription for Children’s Illnesses

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The Indian Academy of Paediatrics (IAP), Kerala chapter, has issued a strong advisory urging parents to avoid self-medicating children and instead seek professional paediatric consultation for managing common illnesses like cough and cold. The academy has also called on healthcare providers to follow rational prescription practices to ensure safe and effective treatment for young patients. The guidance follows a recent directive from the Drugs Controller General of India (DCGI), which prohibits the prescription of cough syrups for children under two years of age. “The DCGI’s directive is a reminder to ensure rational use of medicines, especially in infants and young children,” said Dr. I. Riaz, President of IAP Kerala. “Parents should resist the urge to purchase over-the-counter cough syrups or reuse old prescriptions. For persistent cough, consulting a paediatrician for proper diagnosis and dosage is essential.” The IAP Kerala further advised that combination cough and cold medications should not be prescribed for children below two years, and their use in older children should only follow thorough medical evaluation and careful supervision. Dr. Riaz explained that cough is often a symptom of underlying issues such as asthma, allergies, dehydration, or post-nasal drip. Most cases of acute cough in children are self-limiting and resolve without medication. For children above six months, paediatricians may prescribe antihistamines or bronchodilators when clinically necessary, using correct doses and minimal duration. When treating asthma or wheezing-related cough, bronchodilators are best administered through a Metered Dose Inhaler (MDI) with spacer, a method both safe and effective for children. The academy emphasized non-drug measures—like adequate hydration, rest, saline nasal drops, and supportive care—as the first line of treatment for most childhood coughs. “All coughs are not the same, and parents must avoid repeating old prescriptions,” Dr. Riaz cautioned. “Medication type, dosage, and duration should always be adjusted as a child grows.” Source: The Hindu

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Kidney Cancer Cases Could Nearly Double Worldwide by 2050: Study

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A new global study warns that kidney cancer cases may almost double over the next quarter century if current health trends continue. Researchers from Europe, the US, and the UK examined data from the Global Cancer Observatory of the International Agency for Research on Cancer, projecting a dramatic surge in both incidence and mortality. In 2022, around 435,000 new cases and 156,000 deaths from kidney cancer were recorded worldwide. By 2050, the figures could rise to nearly 746,000 cases (a 72% increase) and over 304,000 deaths (a 96% rise), according to findings published in European Urology. The rise is linked largely to modifiable risk factors such as obesity, hypertension, diabetes, smoking, and physical inactivity, alongside environmental exposures. While 5–8% of cases are estimated to have a genetic basis, researchers emphasized that more than half of all kidney cancer cases are preventable. “Kidney cancer is becoming a global health challenge. Clinicians and policymakers must brace for this sharp increase,” said senior author Alexander Kutikov, Chair of the Department of Urology at Fox Chase Cancer Center in the US. He noted that lifestyle interventions—including maintaining a healthy weight, controlling blood sugar and blood pressure, and quitting smoking—can substantially reduce risk. The study also revealed wide geographical and gender-based disparities in incidence and survival. Five-year survival rates currently range between 40% and 75%, with wealthier nations expected to benefit from early detection through routine imaging and better access to advanced treatments such as surgery and radiotherapy. The findings add to a broader global concern: a recent Lancet analysis estimated that annual cancer deaths of all types may climb by 75% over the next 25 years. Alarmingly, 40% of these deaths are linked to 44 preventable risk factors, including poor diet, tobacco, and high blood sugar. Source: PTI

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