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Saturday, March 14, 2026 1:08 PM

Diabetes Risk

BMI at Age 10 and Childhood Growth Rate Linked to Higher Risk of Diabetes and Heart Disease: Study

A new study published in Nature Communications has found that body mass index (BMI) at age 10 and overall growth rate between ages one and 18 may play a significant role in determining the risk of developing diabetes, high cholesterol, and heart disease later in life. The research, led by Nicole Warrington, Senior Research Fellow at the University of Queensland, examined how genetic factors influence changes in a child’s BMI over time. According to Warrington, approximately 25 per cent of the variation in children’s body weight trajectories from age one to 18 can be attributed to genetics. She noted that relying solely on population averages to assess child growth may overlook crucial individual genetic differences. The study analysed nearly 66,000 BMI measurements collected from around 6,300 children and adolescents aged between one and 18 years. By tracking growth patterns longitudinally rather than at a single age, researchers were able to better understand how genetics shapes the pace and pattern of growth. Geng Wang, Postdoctoral Research Fellow at the University of Queensland, said the findings may help reassure parents concerned about early weight gain or growth differences in their children. He explained that genetic factors affecting body size in infancy may differ from those influencing body size during adolescence. Importantly, the researchers found that body size differences in early childhood do not necessarily indicate a lifelong risk of obesity. Warrington emphasised that further research is needed to identify the most effective stages in childhood to intervene for preventing obesity or poor growth outcomes in the long term. The data for the analysis was drawn from the “Children of the 90s” study, conducted by the University of Bristol, a long-term research project investigating environmental and genetic influences on health and development. Source: PTI

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Study in India Reveals Link Between Air Pollution and Type 2 Diabetes Risk

News on Health

Air pollution in India has been linked to an increased risk of type 2 diabetes, as revealed in a groundbreaking study published in the BMJ Open Diabetes Research and Care journal. The study, the first of its kind in India, was conducted in Delhi and Chennai, and it found that exposure to elevated levels of fine pollution particles (PM2.5) in the air, which are 30 times thinner than a strand of hair, is associated with higher blood sugar levels and an elevated incidence of type 2 diabetes. While the health impacts of fine particulate matter are known for cardiovascular and cardiometabolic diseases, this study sought to provide evidence from regions with high air pollution levels like India, where noncommunicable diseases are a significant burden. The research team, which included scientists from the Centre for Chronic Disease Control in New Delhi, followed a group of over 12,000 men and women from 2010 to 2017, regularly measuring their blood sugar levels. They also utilized satellite data and air pollution exposure models to assess air quality in the participants’ localities during that period. The results demonstrated that exposure to PM2.5 for just one month led to increased blood sugar levels, and prolonged exposure for a year or more elevated the risk of diabetes. Additionally, for every 10 micrograms per cubic meter (μg/m3) increase in the annual average PM2.5 levels in Delhi and Chennai, the risk of diabetes rose by 22 percent. The study addressed a significant research gap in South Asia, where diabetes is a major health concern, by providing robust exposure assessment and longitudinal data in this population. It underscores the need for tailored, population-specific policies to combat the high diabetes prevalence by reducing ambient air pollution. The research team, which also included scientists from the Public Health Foundation of India, Harvard University, Emory University, the All India Institute of Medical Sciences, and the Madras Diabetes Research Foundation, emphasized the importance of region-specific measures to achieve meaningful public health improvements at the population level.

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