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Wednesday, July 2, 2025 9:25 AM

global health

Highly Contagious COVID-19 Variant NB.1.8.1 Spreads from China to the US

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A newly emerging COVID-19 variant, NB.1.8.1 — known for its high transmissibility and recent surge in China — has now been identified in the United States, including cases in New York City, according to the Centers for Disease Control and Prevention (CDC). The variant was first detected among international travelers entering the U.S. between late March and early April through airports in California, Washington State, Virginia, and New York. Since then, additional infections have been reported in Ohio, Rhode Island, and Hawaii. Although the U.S. case count remains relatively small, public health experts are monitoring the situation closely due to the variant’s rapid spread across Asia, where it has become the leading strain. In Hong Kong, the NB.1.8.1 variant has led to a significant rise in hospital admissions and emergency visits, particularly affecting senior citizens. Reports indicate that within a span of four weeks, the city recorded 81 severe cases and 30 fatalities, primarily among individuals aged 65 and older. Mainland China has also seen a steep increase in COVID-positive patients in emergency departments, along with a spike in hospitalizations. However, Chinese health authorities maintain that the variant does not pose a greater threat than earlier strains. U.S. experts are taking a more cautious stance. Dr. Amy Edwards of Case Western Reserve University noted that while NB.1.8.1 may not result in more severe illness, its rapid transmission is concerning. “There’s a clear increase in hospital activity in places like China and Hong Kong,” she told CBS News. CDC data shows that those carrying the variant had traveled from countries including China, Japan, South Korea, Vietnam, Thailand, France, Spain, and Taiwan — suggesting broader international transmission. NB.1.8.1 presents symptoms similar to prior variants — including fatigue, fever, sore throat, and coughing — but scientists believe it has a “growth advantage,” potentially allowing it to spread more efficiently. Dr. Subhash Verma from the University of Nevada highlighted this increased transmissibility as a cause for concern. In Hong Kong, Dr. Edwin Tsui of the Centre for Health Protection urged vigilance, warning that the variant might be more adept at bypassing existing vaccine defenses. Health officials there are tracking the variant’s evolution in line with World Health Organization (WHO) guidance. The emergence of NB.1.8.1 coincides with changes to U.S. COVID-19 vaccine policy. The CDC recently updated its guidelines, advising against routine vaccination for healthy children and pregnant women. Future booster shots will primarily target high-risk populations, such as the elderly and immunocompromised individuals. Source: NDTV Photo Credit: Reuters

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India Joins Global Pandemic Treaty; PM Emphasizes Role of Global South in World Health

In a landmark step towards bolstering global health security and future pandemic preparedness, India has officially joined other WHO member nations in endorsing the Pandemic Treaty during the 78th World Health Assembly held in Geneva. Addressing the assembly, the Prime Minister highlighted the critical need for inclusive global healthcare, stating, “The future of a healthy world depends on inclusion, and the health of the world depends on how well we care for the most vulnerable, especially in the Global South who are particularly impacted by health challenges.” He also drew attention to India’s domestic strides in public health, mentioning that government health spending has surged while citizens’ out-of-pocket medical costs have declined significantly. He credited this progress to flagship initiatives such as Ayushman Bharat, which extends free healthcare coverage to over 580 million people, and to the proliferation of affordable public pharmacies. “India has established a vast network of Health and Wellness Centres (HWC) that offer screening for major conditions such as cancer, diabetes, and hypertension. India’s digital platform to track vaccination of pregnant women and children is helping to integrate benefits, insurance, records, and information,” the Prime Minister said. The assembly’s primary goal this year was the finalization of the Global Pandemic Treaty, and the Prime Minister commended the efforts of the WHO and all negotiating nations. “India’s initiatives have brought down out-of-pocket expenditure as a percentage of total health expenditure significantly, while government health expenditure has increased considerably,” he added. A WHO statement confirmed the treaty’s adoption during a plenary session of the assembly, which serves as the organization’s highest decision-making body. The treaty was approved by vote in committee, with 124 nations in favor and 11 abstaining. No country formally opposed the agreement. The Pandemic Agreement outlines key principles and strategies to enhance international collaboration in areas like vaccine access, diagnostics, and treatment distribution, all aimed at reinforcing global preparedness and response to health emergencies. However, the agreement was adopted without participation from the United States, a major WHO donor, which had previously halted its funding commitments to the organization earlier this year. Source: Economic Times  

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WHO Prepares for Life After U.S. Exit Amid Deep Budget Cuts and Donor Shift

As the World Health Organization (WHO) prepares for its annual assembly in Geneva starting May 19, a significant shift looms over the global health body: how to navigate a future without its top financial backer, the United States. The week-long gathering, typically a forum for setting health priorities and policy, approving vaccines, and coordinating international disease responses, is this year overshadowed by the U.S. decision to leave the organization. In January, President Donald Trump issued an executive order initiating the year-long withdrawal process on his first day back in office. With the U.S. accounting for roughly 18% of the WHO’s funding, officials are now grappling with how to stretch limited resources. “Our goal is to focus on the high-value stuff,” said Daniel Thornton, WHO’s director of coordinated resource mobilisation. While specifics remain under discussion, internal planning documents seen by Reuters suggest the agency will prioritize its emergency response and medicine approval efforts, while scaling back on training programs and potentially closing offices in high-income countries. Key health guidance on vaccines and diseases such as HIV and obesity is expected to continue. A Western diplomat, speaking anonymously, acknowledged the challenge ahead: “We’ve got to make do with what we have.” WHO staff have already begun budget and personnel cuts in anticipation of the funding shortfall. Though the U.S. remains a member until January 21, 2026, under the legally mandated transition period, signs of a policy reversal are slim. President Trump initially left the door open to rejoining if the organization “clean it up,” but health envoys say no concrete steps have followed. In the meantime, WHO faces an immediate budget gap of $600 million this year, with deeper cuts—up to 21%—expected over the next two years. As the U.S. steps back, China is poised to become the largest contributor of assessed contributions—one of WHO’s key funding streams. China’s share will rise from over 15% to 20% following a 2022 funding restructure. “We have to adapt ourselves to multilateral organisations without the Americans. Life goes on,” said Chen Xu, China’s ambassador to Geneva. The evolving donor landscape has prompted calls for deeper reform. Anil Soni, CEO of the WHO Foundation, questioned whether the organization still needs its vast array of committees or to publish thousands of documents each year. He added that the transition was forcing a reassessment of operations, including whether WHO should handle routine logistics like fuel purchases during crises. Soni emphasized the urgency of sustaining vital programs amid the funding squeeze, noting that the agency is increasingly turning to philanthropies and the private sector for targeted support. The ELMA Foundation, for instance, recently contributed $2 million to support the Global Measles and Rubella Laboratory Network, which includes over 700 labs monitoring infectious disease threats. Alongside pandemic preparedness agreements and an investment round to court new donors, funding will remain the central concern at the Geneva meeting. A WHO manager’s recent request for staff to volunteer as ushers—without extra pay—reflects the broader austerity mindset taking hold. Source: Reuters Photo Credit: Reuters

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Three Million Child Deaths Linked to Drug Resistance: A Global Health Crisis

A recent global study has sounded alarm bells over the escalating threat of antimicrobial resistance (AMR), revealing that 3 million child deaths in 2022 were linked to infections no longer responding to standard antibiotics. The report, compiled by the Murdoch Children’s Research Institute (Australia) and the Clinton Health Access Initiative, highlights how AMR is fast becoming a global health crisis—particularly affecting children in Africa and Southeast Asia. AMR occurs when bacteria, viruses, or fungi evolve to resist the effects of medicines that once worked against them. As a result, common infections become harder—and sometimes impossible—to treat. This “silent pandemic” has been aggravated by the overuse and misuse of antibiotics, especially in countries like India, which has been flagged as a hotspot due to regulatory gaps and easy access to drugs. Key findings include: 3 million global child deaths in 2022 were AMR-related. 752,000 child deaths occurred in Southeast Asia, and 659,000 in Africa. Use of ‘watch antibiotics’ (for serious infections) rose by 126% in Africa and 160% in Southeast Asia from 2019 to 2021. Use of ‘reserve antibiotics’ (last-resort drugs) increased by 125% and 45%, respectively. The study attributes the rise to overcrowded hospitals, poor sanitation, lack of diagnostic access, and weak antimicrobial stewardship. It also underscores the slow pace of new antibiotic development, which further reduces treatment options for resistant infections. Experts recommend a “One Health” approach, integrating data on how infections spread among humans, animals, and the environment. They also urge stronger national policies, hospital-level antibiotic regulation, and the use of real-time health data to guide responsible treatment decisions. With the World Health Organization already warning about AMR’s impact on mortality and health systems, the report stresses that immediate action is critical to prevent a catastrophic rise in untreatable infections among the most vulnerable—our children. Source: Indiatoday

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Gennova Biopharma Partners with CEPI to Develop mRNA Nipah Vaccine

Gennova Biopharmaceuticals, a subsidiary of Emcure Pharmaceuticals, has announced a partnership with the Coalition for Epidemic Preparedness Innovations (CEPI) to develop a self-amplifying mRNA (saRNA) vaccine for the Nipah virus. The collaboration has secured up to $13.38 million in funding from CEPI to accelerate research and development. Innovative Approach to Vaccine Development As part of this initiative, Gennova will work with the Houston Methodist Research Institute (HMRI), a CEPI partner based in the United States, to integrate artificial intelligence (AI) into vaccine design. AI-driven analysis will be used to identify optimal vaccine targets, enhancing immune response efficiency. Clinical trials are set to begin in India, where Nipah outbreaks have previously occurred. The Nipah Virus Threat Nipah virus, a highly lethal pathogen from the Paramyxovirus family, has caused multiple outbreaks in South and Southeast Asia, with a fatality rate of up to 75%. Though outbreaks have been geographically limited, the virus’s natural reservoir—fruit bats—inhabits regions home to over two billion people, making it a serious global health concern. CEPI’s Commitment to Global Health Kent Kester, Executive Director of Vaccine R&D at CEPI, emphasized the urgency of the project, stating: “With no approved vaccines or specific treatments for Nipah, CEPI is leading the global effort to develop countermeasures. Gennova’s saRNA technology could not only help fight Nipah but also enhance pandemic preparedness, enabling rapid responses within 100 days of identifying a new viral threat.” The Advantage of saRNA Vaccines Unlike traditional mRNA vaccines, which introduce pre-made antigenic proteins, saRNA vaccines provide genetic instructions that enable the body’s own cells to produce these proteins. This approach enhances the immune response while requiring lower doses, making it a promising platform for future vaccine development. A Long-Term Collaboration Gennova’s partnership with CEPI is not new. In August 2023, CEPI granted the company $3.6 million to optimize its saRNA technology for developing vaccines against unknown pathogenic threats, often referred to as Disease X. Sanjay Singh, CEO of Gennova Biopharmaceuticals, commented on the collaboration: “By harnessing our saRNA platform, we aim to develop a next-generation Nipah vaccine. This partnership sets a new benchmark for rapid vaccine development while ensuring equitable access and strengthening global health security.” Ensuring Equitable Access CEPI has invested over $100 million in Nipah vaccine research. Through this collaboration, Gennova has pledged to uphold CEPI’s Equitable Access Policy, ensuring that the vaccine, if successfully developed, will be made available first to at-risk populations at an affordable price. The agreement also includes provisions for technology transfer, which could support future vaccine development efforts against emerging infectious diseases.

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China Reports Decline in HMPV Cases Amid Global Watch

Decline in HMPV Infections in China Chinese health officials report a decline in human metapneumovirus (HMPV) cases in northern provinces, alleviating fears of a potential pandemic. Wang Liping, a representative from the Chinese Center for Disease Control and Prevention, stated that positive cases among children under 14 have started to decrease. This update comes as images circulating online suggested overcrowded hospitals in the region, a claim countered by officials citing no significant shortage of medical resources. Gao Xinqiang of the Health Commission clarified that rising patient numbers in fever clinics reflect improved detection methods rather than an actual surge in infections. WHO Monitoring Global HMPV Trends The World Health Organization (WHO) confirmed that no reports of unusual HMPV outbreaks have been received globally, ensuring that monitoring efforts remain intact. India Prepares for Potential Outbreaks India has reported 17 HMPV cases across several states, including Gujarat (5 cases), Maharashtra and West Bengal (3 cases each), Karnataka and Tamil Nadu (2 cases each), and Assam and Puducherry (1 case each). Health authorities in India emphasize that there is no immediate cause for concern but are preparing for potential outbreaks. About HMPV HMPV, related to the respiratory syncytial virus, typically causes mild cold-like symptoms but can lead to severe respiratory infections in vulnerable populations, such as young children, the elderly, and those with weakened immune systems. Key Challenges: No Vaccines or Specific Treatments: Currently, there are no vaccines or targeted treatments available for HMPV. Global Vigilance Required: Improved detection methods help track the virus but emphasize the need for global preparedness. This developing story highlights the importance of proactive monitoring and readiness in addressing emerging health concerns. Source: newsbytesapp Photo Credit : newsbytesapp

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Over 1 in 5 Adults Worldwide Infected with Genital Herpes: WHO

According to the World Health Organization (WHO), over 846 million people aged 15 to 49, or more than one in five individuals in this age group, are living with genital herpes infections globally. These findings, published in the journal Sexually Transmitted Infections, highlight the widespread nature of the infection and underscore the urgent need for improved prevention, treatment, and vaccine development. Each year, an estimated 42 million people contract a new genital herpes infection, equating to one new case every second. While many infections are asymptomatic, over 200 million individuals in 2020 experienced painful genital sores and blisters, often requiring repeated medical visits. Dr. Meg Doherty, WHO’s Director of Global HIV, Hepatitis, and STI Programmes, emphasized the strain on global health systems: “Genital herpes causes pain and distress for millions, and better prevention and treatment options are critical to controlling its spread and reducing its health impacts, including its link to an increased risk of HIV transmission.” The study estimates 520 million people have genital HSV-2, responsible for 90% of symptomatic cases and associated with a three-fold higher HIV risk. An additional 376 million are infected with genital HSV-1, which is increasingly transmitted during adulthood due to declining childhood oral infections. Herpes infections carry significant social and economic burdens. Stigma often silences discussions about the infection, and healthcare costs and productivity losses are estimated at $35 billion annually. WHO advocates consistent condom use and avoiding sexual contact during active outbreaks to reduce transmission. It also recommends HIV testing for individuals with genital herpes and pre-exposure prophylaxis when needed. Research into vaccines and new treatments remains a priority, as these advancements could significantly improve global health outcomes and reduce the stigma surrounding herpes infections. Source: World Health Organization Photo Credit: World Health Organization

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Ministry of Ayush to Celebrate 9th Ayurveda Day with Focus on Global Health Innovations

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The Ministry of Ayush is set to celebrate the 9th Ayurveda Day on October 29 at the All India Institute of Ayurveda (AIIA) in New Delhi. This year’s theme, Ayurveda Innovations for Global Health, highlights the expanding role of Ayurveda in addressing global health challenges. The event is expected to draw participation from over 150 countries, reflecting Ayurveda’s growing international recognition. Minister of State for Ayush, Prataprao Jadhav, emphasized the significance of Ayurveda Day as a global movement. He noted that this year’s theme underscores the contributions of Ayurveda to global health advancements. The government aims to promote Ayurveda as a robust medical system worldwide, benefiting public health across borders. In discussing the Ministry’s recent initiatives, Jadhav pointed to efforts to make Ayurveda knowledge more accessible to the public through digital platforms under the Ayush Grid. This includes innovative programs such as the Ayurgyan Scheme, the Ayush Research Portal, and the Namaste Portal. He further highlighted that Ayurveda is currently recognized in 24 countries, with Ayurveda products being exported to over 100 nations. The celebration of Ayurveda Day demonstrates the Ministry’s commitment to advancing traditional medicine in a modern context, while promoting holistic well-being and health innovation on a global scale. Source: newsonair. gov

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Melinda French Gates Launches $250 Million Initiative to Address Global Women’s Health Crisis

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Melinda French Gates has unveiled a $250 million global initiative aimed at tackling critical issues in women’s health, including maternal mortality, malnutrition, and access to reproductive healthcare. The initiative, called Action for Women’s Health, seeks to provide funding to organizations addressing these challenges, particularly in underserved communities. The announcement comes amid growing concerns over rising maternal deaths and healthcare deserts, especially following the U.S. Supreme Court’s decision to overturn Roe v Wade in 2022. In an interview with The Guardian, French Gates expressed alarm over the healthcare disparities faced by women worldwide. “More than 700 women die from childbirth every day, and over one billion women and girls suffer from malnutrition. These numbers are unacceptable,” she said. The new initiative invites women’s health-focused organizations globally to apply for grants of up to $5 million to help scale their efforts. French Gates emphasized the urgency of addressing these issues, especially with the upcoming U.S. elections, which she described as pivotal for women’s rights. “There is so much at stake for women and families in this election, and we need a leader who will fight for women’s rights, especially their access to reproductive care,” she stated, publicly endorsing U.S. Vice President Kamala Harris. This initiative is part of a broader $1 billion commitment from French Gates over the next two years to support women’s health and rights globally. She has called on community-driven organizations with proven track records to apply for funding, stressing that women’s health is foundational to the well-being of society as a whole. Source: Business Standard

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WHO and FIND Join Forces to Accelerate Diagnostic Innovation and Access

FIND and the World Health Organization (WHO) have signed a new Memorandum of Understanding (MoU) that lays the foundation for accelerating innovation and achieving equitable access to quality diagnostics for people globally. One year on from the historic resolution to strengthen diagnostics, and with FIND as co-lead of the Access to COVID-19 Tools (ACT) Accelerator diagnostics pillar, this new agreement marks a step change in a strengthened partnership between WHO and FIND to speed up both innovation and access to diagnostics, supporting countries to implement the World Health Assembly (WHA) Resolution on diagnostics. “We are proud to be signing this MoU with WHO, as quality and accessible diagnostic testing is the backbone of health systems, primary healthcare and health security,” said Dr. Ayoade Alakija, Board Chair of FIND. “At a time when there have been three cases of H5N1 avian flu spillover events from cows to humans in the last month and an outbreak of mpox in the Democratic Republic of the Congo, the importance of diagnostic testing to identify outbreaks and quash them before they become major epidemics or even pandemics has never been more critical.” This new agreement establishes FIND as the key strategic partner for diagnostics, working with WHO and others to address a number of priority areas including antimicrobial resistance, infectious diseases like HIV, malaria and tuberculosis, and noncommunicable diseases like hypertension, heart disease, cervical cancer and diabetes. Signed on 1 June 2024 at a ceremony attended by Dr. Tedros Adhanom Ghebreyesus, Dr. Yukiko Nakatani (Assistant Director-General), and Dr. Ayoade Alakija (Board Chair of FIND), the MoU will also see the two organizations building new avenues to share knowledge and scale up critical activities to accelerate access to life-saving diagnostics. The signing of this MoU formalizes a long-standing partnership between WHO and FIND and marks a major milestone in the journey towards better health and well-being across the world. By leveraging the strengths and expertise of both WHO and FIND, this partnership promises to drive innovation on diagnostic tests and also improve access to the tests to reduce health inequalities, ultimately leading to a healthier future for people everywhere.  

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