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Thursday, November 13, 2025 4:15 AM

maternal health

Planned C-Sections May Increase Childhood Leukaemia Risk, Study Finds

A recent study from Sweden suggests that babies delivered through planned caesarean sections may face a higher risk of developing leukaemia—specifically acute lymphoblastic leukaemia (ALL)—compared to those born via emergency C-sections or vaginal delivery. The study, conducted by researchers at Karolinska Institutet and published in The International Journal of Cancer, analysed health data from nearly 2.5 million children born between 1982–1989 and 1999–2015, using Sweden’s Medical Birth Register. Of the total births, around 375,000 (15.5%) were delivered through C-sections. Among these, 1,495 children were later diagnosed with leukaemia. The researchers found that children born via C-section had a 7% higher risk of developing acute lymphoblastic leukaemia compared to those born vaginally. Notably, when comparing types of C-sections, those delivered by planned (elective) C-section faced a 21% increased risk of ALL than those born through emergency C-sections. One possible explanation, the study suggests, lies in the differing levels of exposure to beneficial bacteria and birth stress. Emergency C-sections typically occur after the onset of labour, and if the amniotic sac has ruptured, the baby is partially exposed to vaginal microbes and the physical stress of labour—factors that might positively influence immune development. Planned C-sections, on the other hand, are often scheduled before labour begins, limiting such exposure. Lead researcher Christina-Evmorfia Kampitsi emphasized that the findings shouldn’t cause undue concern for mothers who require medically necessary C-sections. However, she noted that the results support existing research indicating that planned C-sections may also be linked to increased risks of asthma, allergies, and type 1 diabetes in children. “These insights strengthen the case for carefully evaluating the necessity of non-medically indicated planned caesarean deliveries,” Kampitsi said. The study contributes to a growing body of evidence exploring how early-life exposures—especially those related to birth methods—may influence long-term health outcomes, including the development of childhood cancers such as acute lymphoblastic leukaemia. Source: PTI

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India Leads Global Preterm Births in 2020, Lancet Study Reveals

In 2020, India witnessed the highest number of preterm births globally, with a staggering 3.02 million cases, constituting over 20 percent of all premature births worldwide, as revealed by a study published in The Lancet journal. This research, conducted by experts from the World Health Organization (WHO), the United Nations Children’s Fund (UNICEF), and the London School of Hygiene and Tropical Medicine, UK, further disclosed that more than half of all premature births in 2020 occurred in just eight countries. Following India, the countries with the highest preterm birth rates were Pakistan, Nigeria, China, Ethiopia, Bangladesh, the Democratic Republic of the Congo, and the United States, according to the researchers. The notable prevalence of preterm births in these regions is partly attributable to their substantial population sizes, high numbers of total births, and underdeveloped healthcare systems that struggle to provide high-quality family planning, antenatal care, and childbirth services to all those in need. Globally, approximately 13.4 million babies were born prematurely in 2020, with nearly one million succumbing to complications associated with preterm birth. This data equates to roughly one in ten babies being born prematurely, before completing 37 weeks of pregnancy worldwide. Given that prematurity ranks as the leading cause of child mortality in their early years, there is an urgent need to bolster both preterm infant care and preventative measures, particularly focusing on maternal health and nutrition to enhance child survival, emphasize the authors of the study. Furthermore, preterm birth significantly increases the likelihood of major illnesses, disabilities, developmental delays, and even chronic diseases like diabetes and heart conditions in adulthood for those who survive. This study derives its estimates from data that is representative of populations and national statistics, enabling internationally comparable assessments for the year 2020. It highlighted that India had the highest incidence of preterm births in 2020, totalling 3.02 million cases, accounting for over a fifth of all preterm births worldwide. While most high preterm birth rates were observed in low and middle-income nations, rates of 10 percent or higher were also evident in high-income countries such as Greece and the United States. Within South Asia, Bangladesh reported the highest preterm birth rate in 2020 at 16.2 percent, followed by Pakistan at 14.4 percent, and India at 13.0 percent. In Latin America, the rates ranged from 5.8 percent in Nicaragua to 12.8 percent in Suriname. As birth registration and facility-based deliveries have increased, data on the prevalence of preterm births has improved. Nevertheless, there are still 92 countries lacking sufficient nationally representative data. Consequently, the authors call for sustained efforts to enhance data availability, quality, and sharing to better target support and action where it is most needed. Dr. Anshu Banerjee, Director of Maternal, Newborn, Child, and Adolescent Health and Ageing at WHO, emphasized the vulnerability of preterm babies to life-threatening health complications and the necessity for dedicated care and attention. He stressed the urgency of substantial investments in services supporting preterm infants and their families, as well as a heightened focus on prevention, particularly ensuring access to quality healthcare before and during pregnancies. The researchers underscored that preterm birth is not exclusive to low and middle-income countries, as the data clearly reveals its impact on families worldwide, including some high-income countries such as Greece (11.6 percent) and the United States (10 percent).

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