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Thursday, April 30, 2026 5:46 AM

NB.1.8.1 variant

Highly Contagious COVID-19 Variant NB.1.8.1 Spreads from China to the US

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A newly emerging COVID-19 variant, NB.1.8.1 — known for its high transmissibility and recent surge in China — has now been identified in the United States, including cases in New York City, according to the Centers for Disease Control and Prevention (CDC). The variant was first detected among international travelers entering the U.S. between late March and early April through airports in California, Washington State, Virginia, and New York. Since then, additional infections have been reported in Ohio, Rhode Island, and Hawaii. Although the U.S. case count remains relatively small, public health experts are monitoring the situation closely due to the variant’s rapid spread across Asia, where it has become the leading strain. In Hong Kong, the NB.1.8.1 variant has led to a significant rise in hospital admissions and emergency visits, particularly affecting senior citizens. Reports indicate that within a span of four weeks, the city recorded 81 severe cases and 30 fatalities, primarily among individuals aged 65 and older. Mainland China has also seen a steep increase in COVID-positive patients in emergency departments, along with a spike in hospitalizations. However, Chinese health authorities maintain that the variant does not pose a greater threat than earlier strains. U.S. experts are taking a more cautious stance. Dr. Amy Edwards of Case Western Reserve University noted that while NB.1.8.1 may not result in more severe illness, its rapid transmission is concerning. “There’s a clear increase in hospital activity in places like China and Hong Kong,” she told CBS News. CDC data shows that those carrying the variant had traveled from countries including China, Japan, South Korea, Vietnam, Thailand, France, Spain, and Taiwan — suggesting broader international transmission. NB.1.8.1 presents symptoms similar to prior variants — including fatigue, fever, sore throat, and coughing — but scientists believe it has a “growth advantage,” potentially allowing it to spread more efficiently. Dr. Subhash Verma from the University of Nevada highlighted this increased transmissibility as a cause for concern. In Hong Kong, Dr. Edwin Tsui of the Centre for Health Protection urged vigilance, warning that the variant might be more adept at bypassing existing vaccine defenses. Health officials there are tracking the variant’s evolution in line with World Health Organization (WHO) guidance. The emergence of NB.1.8.1 coincides with changes to U.S. COVID-19 vaccine policy. The CDC recently updated its guidelines, advising against routine vaccination for healthy children and pregnant women. Future booster shots will primarily target high-risk populations, such as the elderly and immunocompromised individuals. Source: NDTV Photo Credit: Reuters

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New COVID-19 Subvariants NB.1.8.1 and LF.7 Detected in India: INSACOG Report

India has recorded the presence of two newly emerging COVID-19 subvariants—NB.1.8.1 and LF.7—according to recent data released by the Indian SARS-CoV-2 Genomics Consortium (INSACOG). While these variants are currently categorized as Variants Under Monitoring by the World Health Organization (WHO), they have been linked to the recent surge in COVID-19 cases across China and parts of Asia. As per the INSACOG data, a single case of NB.1.8.1 was identified in Tamil Nadu in April, while four cases of LF.7 were reported from Gujarat in May 2025. Despite these new detections, the dominant strain circulating in India remains JN.1, accounting for approximately 53% of the tested samples. It is followed by BA.2 (26%) and other Omicron-related variants (20%). Preliminary assessments by WHO suggest that NB.1.8.1 poses a low global public health risk, but the subvariant carries spike protein mutations—A435S, V445H, and T478I—that may enhance both transmissibility and the ability to evade immune responses. As of May 19, India reported 257 active COVID-19 cases. A high-level review meeting was recently convened, chaired by the Director General of Health Services, with participation from the ICMR, National Centre for Disease Control, and other leading health agencies to monitor the evolving situation. Meanwhile, certain states have shown localized spikes. Delhi reported 23 new cases, Andhra Pradesh had four, Telangana confirmed one, and Bengaluru recorded a positive case in a nine-month-old infant, reflecting a steady rise over the last 20 days. Kerala, in particular, reported 273 cases in May alone. Source: PTI

New COVID-19 Subvariants NB.1.8.1 and LF.7 Detected in India: INSACOG Report Read More »