Omicron

India has recorded the presence of two newly emerging COVID-19 subvariants—NB.1.8.1 and LF.7—according to recent data released by the Indian SARS-CoV-2 Genomics Consortium (INSACOG). While these variants are currently categorized as Variants Under Monitoring by the World Health Organization (WHO), they have been linked to the recent surge in COVID-19 cases across China and parts of Asia. As per the INSACOG data, a single case of NB.1.8.1 was identified in Tamil Nadu in April, while four cases of LF.7 were reported from Gujarat in May 2025. Despite these new detections, the dominant strain circulating in India remains JN.1, accounting for approximately 53% of the tested samples. It is followed by BA.2 (26%) and other Omicron-related variants (20%). Preliminary assessments by WHO suggest that NB.1.8.1 poses a low global public health risk, but the subvariant carries spike protein mutations—A435S, V445H, and T478I—that may enhance both transmissibility and the ability to evade immune responses. As of May 19, India reported 257 active COVID-19 cases. A high-level review meeting was recently convened, chaired by the Director General of Health Services, with participation from the ICMR, National Centre for Disease Control, and other leading health agencies to monitor the evolving situation. Meanwhile, certain states have shown localized spikes. Delhi reported 23 new cases, Andhra Pradesh had four, Telangana confirmed one, and Bengaluru recorded a positive case in a nine-month-old infant, reflecting a steady rise over the last 20 days. Kerala, in particular, reported 273 cases in May alone. Source: PTI