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Thursday, February 19, 2026 9:49 AM

Oxidative Stress

Daily Almond Intake of 60 Grams Found to Shield DNA and Combat Oxidative Stress

Almonds may be more than just a crunchy snack — they could be a powerful ally in protecting your health at the cellular level. New research suggests that consuming at least 60 grams of almonds a day can significantly reduce oxidative stress and safeguard DNA from damage. Oxidative stress, caused by an overload of harmful free radicals, accelerates aging, inflammation, and chronic disease risk. Almonds, rich in vitamin E, antioxidants, flavonoids, and healthy fats, act as natural defenders, helping neutralize these free radicals and strengthening the body’s resilience. According to the study, individuals who included over 60 grams of almonds in their daily diet showed notable improvements in antioxidant activity and reduced markers of oxidative stress. This directly translates into better DNA protection, healthier cells, and potentially slower signs of aging. Earlier clinical evidence also supports this. A landmark randomized trial with young male smokers who consumed 84 g of almonds daily recorded a 28% drop in oxidative DNA damage, a 34% reduction in lipid peroxidation, and a 23% decline in DNA strand breaks, proving almonds’ protective benefits even under high-stress conditions. The “60 g threshold” is now being recognized as a key benchmark. That’s about 40–45 almonds per day, roughly two servings — enough for the bioactive compounds in almonds to activate their strongest protective effects. While smaller amounts still offer health benefits, crossing this intake level seems to unlock greater antioxidant potential. Beyond heart and brain health, almonds are emerging as a natural superfood for DNA protection. Their vitamin E helps shield cell membranes, while polyphenols and flavonoids reduce inflammation and support vascular health. Together, they slow down cellular wear and tear linked to aging, cancer, diabetes, and cardiovascular disease. Experts emphasize that consistency is crucial. Incorporating almonds daily — whether eaten raw, roasted, blended into smoothies, or sprinkled over meals — makes it easy to hit the 60 g mark. This growing body of evidence reinforces almonds as more than a nutritious snack: they are a long-term investment in wellness, helping preserve genetic material, reduce disease risks, and support healthier aging. Source: TOI

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Genefitletics Enhances Platform to Decode Cellular Health

Indian biotech startup Genefitletics has unveiled a major update to its health platform, enabling it to assess the condition of individual cells by detecting the expression of key biological signals. This advancement allows for early identification of chronic diseases—often in their asymptomatic stages—through a combination of next-generation sequencing and machine learning. According to the company, the upgraded platform now generates a “cellular health score” by analyzing markers linked to inflammation, mitochondrial function, immune activity, cellular stress, and senescence. This empowers users to monitor and improve their internal health at the cellular level. Additional capabilities include evaluations related to triglyceride regulation, risk indicators for irritable bowel disease, and a dynamic feedback system that shows how nutritional and lifestyle interventions influence biological pathways in real time. Sushant Kumar, Founder and CEO of Genefitletics, explained, “Our proprietary platform, PROTEBA, is trained on an extensive dataset—over 12 billion molecular data points, 45 million phenotype records, more than 35,000 peer-reviewed scientific publications, and continuously updated clinical insights. It now enables us to track the activity of biological pathways involved in cellular inflammation, energy inefficiency, aging, and various types of cellular stress—including oxidative, genotoxic, hypoxia-induced, and protein-misfolding stress.” This update marks a significant leap in personalized health monitoring, providing deeper insight into cellular functions and the impact of daily choices on long-term health. Source: ETHealthWorld

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Indian Scientists Pioneer Innovative Nanoparticles for Detecting and Destroying Cancer Cells

Indian scientists from the Indian Institute of Science (IISc) have achieved a major breakthrough in cancer research with a novel approach for both detecting and eliminating cancer cells. Their innovation involves the creation of hybrid nanoparticles made from a combination of gold and copper sulphide. These nanoparticles have the unique ability to eradicate cancer cells by generating heat when exposed to light and also facilitate their identification through sound waves. These hybrid nanoparticles possess three key properties: photothermal capabilities, oxidative stress induction, and photoacoustic characteristics. When these particles come into contact with light, they absorb it and produce heat, effectively destroying cancer cells. Furthermore, they generate harmful singlet oxygen atoms that contribute to the cancer cell’s demise. In addition to their therapeutic potential, these nanoparticles also have diagnostic applications. They can absorb light and produce ultrasound waves, making it possible to detect cancer cells with high precision. This diagnostic capability could enhance the accuracy of cancer diagnosis because sound waves scatter less than light when passing through tissues, providing clearer images and more precise measurements of oxygen levels in tumors. One notable aspect of this innovation is its ability to overcome a limitation of previously developed nanoparticles: their size. Through a unique reduction technique, the IISc researchers managed to deposit tiny gold seeds onto the surface of copper sulphide, resulting in hybrid nanoparticles measuring less than 8 nm. These minuscule particles have the potential to navigate through tissues effectively, reach tumors, and exit the human body naturally without accumulating. These nanoparticles have undergone testing in laboratory settings using lung and cervical cancer cell lines. The next phase for the IISc team is to translate these promising results into clinical development, marking a significant advancement in the battle against cancer.

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