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Friday, September 18, 2026 7:14 AM

Public Health

India Could Get Indigenous Dengue Vaccine by End of 2027: ICMR DG

India could have its own indigenous dengue vaccine by the end of next year, provided the ongoing follow-up of participants in the vaccine’s Phase 3 clinical trial progresses as expected, ICMR Director General Rajiv Bahl said. Speaking in Kolkata on Sunday, Bahl said the randomised Phase 3 trial is being conducted across 20 institutes and involves more than 13,000 volunteers. For every two participants who received the vaccine, one was administered a placebo. Nearly a year of follow-up has been completed, and researchers are hopeful of unblinding the trial results by the end of next year. NIRBI Director Santasabuj Das said the institute, formerly known as NICED, is among the centres participating in the nationwide trial and is monitoring 674 enrolled volunteers. DengiAll, described as India’s first indigenous single-dose dengue vaccine, is designed to provide protection against all four dengue virus serotypes circulating in the country. However, relatively low dengue transmission this year could delay the process of obtaining enough data to unblind the trial. Bahl also highlighted the importance of Kangaroo Mother Care (KMC) during the fourth Dilip Mahalanabis Oration organised by the Liver Foundation West Bengal. KMC involves prolonged skin-to-skin contact between a newborn and the mother and has been shown to improve outcomes for vulnerable newborns. Reflecting on the legacy of late public health pioneer Dilip Mahalanabis, Bahl highlighted the development of sick newborn care units and the evolution of the model into Mother Newborn Care Units, which promote zero separation between mothers and preterm or sick newborns. Public health activist and hepatologist Abhijit Chowdhury said Mahalanabis demonstrated how simple, evidence-based healthcare interventions can have a transformative impact on human lives, inspiring the foundation to organise an annual oration in his memory. Source: Economic Times

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Jharkhand on high alert over H1N1 as Health Minister orders hospitals to reserve beds, intensify surveillance

The Jharkhand Health Department has stepped up preparedness across the state amid concerns over potential H1N1, or swine flu, cases, with Health Minister Irfan Ansari directing officials to strengthen surveillance, testing and hospital readiness. Ansari chaired a high-level review meeting with senior health officials, medical college authorities and district Civil Surgeons, directing surveillance teams to closely monitor suspected cases and ensure their prompt reporting. Assuring residents that there was no need to panic, the Health Minister said H1N1 is a respiratory viral infection and that most patients recover with timely diagnosis and appropriate treatment. He urged people to seek medical attention promptly if they develop symptoms. As part of the preparedness measures, authorities have been asked to reserve 10 additional beds at every medical college hospital, including Rajendra Institute of Medical Sciences (RIMS) in Ranchi, as well as at all district Sadar Hospitals. Hospitals have also been instructed to maintain sufficient stocks of medical oxygen and essential medicines, strengthen diagnostic facilities and ensure ICU and HDU readiness. Adequate trained medical and paramedical staff are also to be kept available to handle any surge in cases. The department will intensify monitoring of Influenza-Like Illness (ILI) and Severe Acute Respiratory Infection (SARI) cases to facilitate early detection and treatment. Surveillance will also be increased at airports, railway stations and bus stands, where health teams will assess travellers showing symptoms such as fever, cough, sore throat or breathing difficulties and arrange testing and treatment when necessary. Ansari said the entire health system was being kept on alert and that the government was continuously monitoring the situation. He urged people to remain cautious, follow preventive measures and consult healthcare professionals without delay if symptoms develop. Source: ANI

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More Than 16,000 Ebola Vaccine Doses Arrive in Outbreak-Hit DRC

More than 16,000 doses of the Ervebo Ebola vaccine arrived in the Democratic Republic of Congo (DRC) on Friday, August 21, as the country battles its deadliest Ebola outbreak, according to an AFP journalist at the scene. A total of 16,250 doses were delivered by plane to Kinshasa, forming part of the 70,000 Ervebo doses made available to the DRC by the World Health Organisation (WHO). Of the total allocation, 20,000 doses are earmarked for a clinical trial, while 50,000 will be administered to frontline and healthcare workers. The DRC declared its 17th Ebola outbreak on May 15, although health officials believe the virus had been circulating for several weeks before the announcement. The outbreak has affected areas in the country’s north and east, where limited state presence, weak healthcare infrastructure and the presence of armed groups have complicated the response. According to the latest figures from Congolese authorities, the outbreak has resulted in 5,290 confirmed cases and 2,516 deaths. Julien Harneis, the UN’s senior Ebola coordinator, warned on Friday that the outbreak was “growing exponentially”. The Ervebo vaccine, developed by pharmaceutical company Merck, is approved for protection against the Zaire strain of Ebola but has not been approved for the Bundibugyo strain currently circulating in the DRC. WHO experts are yet to establish whether it can protect humans against the strain, although preliminary evidence, including animal studies, indicates that it may provide some level of protection. DRC Health Minister Samuel Roger Kamba said Ervebo had already been deployed during previous outbreaks, including extensively during the 2018-2020 Ebola epidemic. WHO vaccine experts this month recommended conducting a large-scale human trial to determine whether Ervebo can provide cross-protection against the Bundibugyo strain. The trial is expected to provide crucial evidence as authorities seek to contain the rapidly expanding outbreak. Researchers are also working on vaccines specifically designed to target the Bundibugyo strain. Moderna is developing an mRNA-based candidate, while another vaccine is being developed by the University of Oxford. Singapore-based Hilleman Laboratories is also set to develop an “rVSV Bundibugyo” vaccine, which WHO has described as the most promising candidate. Ebola spreads primarily through contact with infected bodily fluids and can cause severe fever and other serious symptoms. The virus has killed more than 15,000 people across Africa over the past five decades. Source: AFP  

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Tamil Nadu to Launch Health Insurance Scheme for Elderly, Announces Major Healthcare Reforms

The Tamil Nadu government has announced a series of healthcare reforms, including a new health insurance scheme for senior citizens, annual free health check-ups for people aged 30 and above, and a major expansion of medical infrastructure and healthcare workforce. The announcements were made in the Tamil Nadu Assembly as the government outlined plans to modernise the State’s healthcare system and address emerging and future health challenges. The 87-year-old Tamil Nadu Public Health Act, 1939, will be replaced with a new comprehensive legislation designed to address contemporary healthcare requirements. The proposed law will also include a provision making unsupervised home births outside hospitals a punishable offence. The government also plans to establish ‘TN Medicity’, a world-class integrated healthcare hub bringing together clinical services, medical research, medical tourism and AYUSH facilities. An initial allocation of ₹10 crore will be made to prepare the Detailed Project Report for the proposed project. Free Annual Health Checks for People Above 30 Under the proposed ‘Nalam 360 – Annual Free Health Check-up for All’ initiative, residents aged 30 years and above will receive 14 basic health tests every year at no cost. The programme will be implemented across 1,257 government healthcare facilities in Tamil Nadu. The tests will cover key health indicators, including blood pressure, ECG, haemoglobin, complete haemogram, random blood sugar, urea, creatinine, total cholesterol, serum bilirubin, urine albumin and VIA screening. For the first time in the State, the Health Department will also introduce Home Based Diagnostic Services in metropolitan areas. The initiative will facilitate sample collection and testing at people’s homes through a public-private partnership model. New Health Policy and Institutions The government will introduce a ‘Positive Health Policy’ aimed at promoting holistic health and wellbeing at the individual, family and community levels. A ‘Nalam 360’ mobile application will accompany the initiative. Another proposed legislation, the ‘TN Institutions of State Importance in Health Care Act’, will facilitate the creation of institutions of State importance focused on delivering advanced and world-class medical services. Expansion of Healthcare Workforce To address staffing requirements, the government will create 2,500 permanent staff nurse positions. Existing nurses working on consolidated pay will also be absorbed into regular time-scale positions. In addition, 1,695 nursing posts on consolidated pay will be created at an estimated cost of ₹42.72 crore. The Medical Services Recruitment Board will recruit 3,594 medical personnel across 24 categories, including pharmacists, nursing assistants, village health nurses and ophthalmic assistants. The Health Department will also create 284 temporary super-speciality posts across 25 disciplines, including neurology, cardiology and nephrology. These positions will be placed on time-scale pay and are intended to strengthen access to specialised healthcare at the district level. The posts will also provide opportunities for doctors completing postgraduate medical education each year, particularly those posted in government hospitals under bond conditions. The government has further announced several infrastructure initiatives, including construction of new hospital buildings and procurement of additional medical equipment, as part of its broader effort to strengthen healthcare delivery across Tamil Nadu. Source: The Hindu

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India’s Growing Metabolic Health Crisis: Obesity, Diabetes and Hypertension

For years, India’s biggest health challenges were closely associated with infectious diseases, malnutrition and limited access to healthcare. But the country is now facing another major public-health challenge: a rapidly growing burden of metabolic and non-communicable diseases. Obesity, diabetes, hypertension and abnormal cholesterol levels are increasingly affecting Indians across age groups and income categories. What makes the situation particularly concerning is that these conditions are closely connected. A person with excess weight may develop insulin resistance, which can increase the risk of type 2 diabetes. High blood pressure and abnormal cholesterol can further increase the risk of heart disease and stroke. The problem is no longer confined to older adults. Younger Indians are increasingly exposed to sedentary lifestyles, calorie-dense diets, poor sleep and chronic stress, creating the conditions for metabolic problems much earlier in life. The World Health Organization identifies unhealthy diets, physical inactivity, tobacco use and harmful alcohol consumption as major behavioural risk factors for non-communicable diseases. These behaviours contribute to metabolic changes such as raised blood pressure, high blood glucose, overweight and obesity. The scale of India’s metabolic health problem One of the clearest pictures of India’s metabolic health comes from the ICMR-INDIAB study, a large population-based study covering adults across 31 states and Union Territories. Published in The Lancet Diabetes & Endocrinology in 2023, the study assessed more than 113,000 participants and examined the prevalence of diabetes, prediabetes, hypertension, obesity and other metabolic conditions. The findings estimated that India had around 101 million people living with diabetes, while another 136 million were in the prediabetes category. The study also highlighted substantial levels of hypertension and obesity, with considerable variation between states and between urban and rural populations. This variation is important. India does not have a single metabolic-health profile. Dietary habits, economic conditions, urbanisation, physical activity, genetics and access to healthcare differ significantly from one region to another. Yet the broader direction is clear: metabolic disorders have become a major component of India’s disease burden. Obesity is becoming a public-health issue Obesity is often discussed as an issue of appearance or weight management. Medically, however, excess body fat can have much broader consequences. India’s Ministry of Health and Family Welfare notes that overweight and obesity are important risk factors for conditions including coronary heart disease, hypertension, stroke, type 2 diabetes, fatty liver disease, certain cancers and osteoarthritis. The concern is also spreading to younger generations. In July 2026, reporting based on the World Obesity Atlas 2026 estimated that approximately 41 million children in India were overweight or obese. Around the same time, ICMR-NIN unveiled policy recommendations focused on improving children’s food environments, including measures involving food advertising, labelling, school canteens and the pricing of unhealthy foods. Childhood obesity is particularly concerning because metabolic risk can accumulate over decades. A child who develops unhealthy eating patterns and low physical activity early in life may carry those behaviours into adolescence and adulthood. That does not mean every overweight child will develop diabetes or hypertension. But it does mean that prevention has to begin much earlier than the traditional idea of starting health checks only in middle age. Diabetes: India’s expanding metabolic challenge Diabetes is perhaps the most visible part of India’s metabolic-health crisis. Type 2 diabetes develops when the body becomes resistant to insulin or does not produce enough insulin to maintain healthy blood glucose levels. Genetics can play a role, but lifestyle and environmental factors also influence risk. India’s dietary transition has become an important part of the discussion. A 2025 study based on ICMR-INDIAB data and published in Nature Medicine examined dietary patterns among more than 18,000 adults. It reported associations between higher consumption of low-quality carbohydrates, including refined grains and added sugars, and increased odds of type 2 diabetes, prediabetes and obesity. The study also found that replacing a portion of dietary carbohydrates with protein, particularly from sources such as pulses, legumes and dairy, was associated with lower diabetes risk. This does not mean that carbohydrates are inherently unhealthy or that Indians should eliminate rice or wheat from their diets. Rather, it highlights the importance of diet quality, portion sizes and dietary balance. For many Indians, the issue is not simply the presence of carbohydrates but a dietary pattern dominated by refined grains and added sugars, combined with insufficient protein, fibre, vegetables and other nutrient-dense foods. Hypertension: The silent component of the crisis If diabetes is often associated with blood-sugar testing, hypertension presents a different challenge. High blood pressure can remain undetected for years because many people experience no obvious symptoms. Persistently elevated blood pressure places additional strain on blood vessels and the heart and increases the risk of cardiovascular disease, stroke and kidney problems. India’s National Programme for Prevention and Control of Non-Communicable Diseases includes population-based screening for hypertension and diabetes among people aged 30 years and above. The screening process includes assessment of risk factors, BMI and blood pressure, among other measures. Government data also indicate the scale of the response required. The National NCD portal reported more than 9.36 crore people under treatment for hypertension and diabetes as of June 2026. Importantly, the number of people receiving treatment should not be interpreted as the total number of Indians living with these diseases. It represents people captured within the government’s treatment system. Why are metabolic diseases increasing? There is no single cause. 1. Changing food habits India’s food environment has changed rapidly. Traditional diets have increasingly been supplemented or replaced by packaged foods, sugary drinks, refined carbohydrates, fried foods and highly processed snacks. Convenience has become an important factor, particularly in urban areas where long working hours and commuting leave less time for preparing meals. 2. Physical inactivity Modern work increasingly involves sitting for prolonged periods. Office jobs, commuting, screen-based entertainment and reduced everyday physical activity can result in people expending far fewer calories than previous generations. Regular exercise cannot completely compensate for an unhealthy diet, but physical activity remains an important component of metabolic health. 3. Urbanisation Urbanisation has brought economic opportunity

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India Accounts for Nearly 70% of South Asia’s Childhood Leukaemia Cases: Lancet Study

India bears the highest burden of childhood leukaemia in South Asia, accounting for nearly 70% of all reported cases in the region, according to a new study published in The Lancet. Researchers attribute the high numbers largely to the country’s vast child population, along with challenges in timely diagnosis and access to specialised treatment. An estimated 25,000 to 50,000 children below the age of 15 are diagnosed with leukaemia in India every year. In West Bengal alone, population-based estimates suggest that around 1,000 to 1,800 children develop the disease annually. Data from hospitals such as Chittaranjan National Cancer Institute and NRS Medical College indicate that acute leukaemia represents nearly 39% of all paediatric cancers in the state. Leukaemia remains the most common childhood cancer in India, accounting for nearly 30–40% of all paediatric cancer cases. Among these, Acute Lymphoblastic Leukaemia (ALL) constitutes nearly three-fourths of diagnoses. Dr. Pritam Singha Roy, Consultant Paediatric Oncologist at Tata Medical Centre, said the number of reported cases has increased over the past decade due to improved diagnostic facilities, greater public awareness and government initiatives that have enabled more children to receive timely treatment. Experts note that India primarily tracks new cancer diagnoses rather than the total number of children living with the disease, making incidence data more readily available than prevalence figures. According to Dr. Narendra Agarwal, Haematologist and Bone Marrow Transplant Physician at Rajiv Gandhi Cancer Institute & Research Centre, India’s large population contributes significantly to its high case count, while many neighbouring countries may still have substantial numbers of undiagnosed or unreported cases. He added that delayed diagnosis remains a major concern, although treatment facilities and patient outcomes have improved considerably across the country. The study examined childhood cancer trends across the eight SAARC nations—India, Pakistan, Bangladesh, Sri Lanka, Nepal, Bhutan, Afghanistan and the Maldives—which together are home to nearly 600 million children aged 0–14 years. Researchers estimated that the region recorded 37,716 new childhood cancer cases and 17,698 deaths in 2022. India accounted for 25,939 cases (68.8%), followed by Pakistan with 7,841 cases (20.8%). Leukaemia emerged as the leading childhood cancer across all SAARC countries, representing between 35% and 50% of cases, while central nervous system (CNS) tumours ranked second. The report also highlighted significant disparities in mortality and healthcare access across South Asia, with mortality-to-incidence ratios varying widely among countries. It called for stronger regional collaboration to improve cancer registration systems, expand access to specialised paediatric oncology care and ensure uninterrupted treatment for affected children. Source: TNN

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Almost Every Country Overuses Strong Antibiotics, Fueling Drug Resistance: Lancet Study

A new global study has found that nearly every country is overusing powerful antibiotics that are meant to be reserved for severe infections, raising concerns over the growing threat of antimicrobial resistance (AMR). The findings, published in The Lancet Public Health, suggest that inappropriate use of these medicines is accelerating the spread of drug-resistant bacteria. Researchers from the University of London and other institutions developed a framework to estimate the ideal level and type of antibiotic use for individual countries. They say the tool can help governments assess whether their antibiotic prescribing patterns are appropriate and guide efforts to curb both excessive and inappropriate antibiotic use. The World Health Organization (WHO) categorises antibiotics under its Access, Watch and Reserve (AWaRe) classification. ‘Access’ antibiotics, such as amoxicillin, are recommended as first-line treatments for common bacterial infections. ‘Watch’ antibiotics are stronger drugs that should only be used when standard treatments are ineffective, while ‘Reserve’ antibiotics are considered last-resort medicines for life-threatening drug-resistant infections. In 2024, the United Nations General Assembly endorsed the AWaRe framework as the global standard for antibiotic monitoring and set a target for at least 70% of antibiotic use worldwide to come from the Access category by 2030. However, researchers noted that no country-specific benchmarks had been established until now. The study grouped countries into four clusters based on factors including income levels, infectious disease burden and antibiotic resistance. Using 2019 data, the researchers estimated that around 43 billion antibiotic treatment courses were required globally, averaging approximately one course per person annually. They concluded that nearly 77% of these should ideally come from the Access category, reinforcing the UN’s 70% target. When researchers compared these estimates with actual antibiotic consumption data from 67 countries and territories, they found widespread misuse. Around 72% of the countries consumed more antibiotics overall than necessary, while 99% exceeded the expected use of Watch antibiotics. The analysis also found that more than half of the countries were underusing Reserve antibiotics, suggesting that some patients with serious drug-resistant infections may not be receiving the specialised treatments they require. Additionally, 60% of the countries continued prescribing antibiotics that the WHO no longer recommends. India, which falls under the study’s second cluster, was estimated to require between 9.9 and 14.7 defined daily doses (DDD) per 1,000 inhabitants per day (DID). However, the country’s actual antibiotic use stood at 18.3 DID, with Watch antibiotics accounting for 9.3 DID and Access antibiotics making up only 4.5 DID. The researchers also highlighted a significant global disparity. Low- and middle-income countries, which face a greater burden of infectious diseases and antimicrobial resistance, require relatively higher access to specialised Watch and Reserve antibiotics. Yet, wealthier nations currently consume these medicines at much higher rates. The authors urged governments to adopt stronger national antibiotic stewardship policies that reduce unnecessary prescriptions while ensuring patients with genuine medical needs have timely access to appropriate treatments. Source: PTI

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Poor Muscle Health Along With Obesity May Significantly Raise Type 2 Diabetes Risk: Study

A combination of poor muscle health and excess body fat may substantially increase the risk of developing type 2 diabetes, according to a new study published in the journal Diabetes Care. Researchers found that individuals with sarcopenic obesity—a condition marked by both obesity and reduced muscle mass and strength—face a considerably higher diabetes risk than those affected by either condition alone. The research, led by Zhongyang Guan, a PhD candidate at Curtin University in Australia, analyzed health data from 479,607 participants in the UK Biobank who were free of diabetes at the start of the study. During an average follow-up period of more than 14 years, nearly 32,950 participants developed type 2 diabetes. According to the findings, people with sarcopenic obesity were more than 3.5 times as likely to develop type 2 diabetes compared to individuals with a healthy body composition. They also had a 19% higher risk than people with obesity alone and a 91% higher risk than those with only sarcopenia. The study revealed that nearly 15% of participants with sarcopenic obesity developed type 2 diabetes within 10 years, compared with around 11% of those with obesity alone and only 3% of individuals without obesity or sarcopenia. Researchers also observed that the association between sarcopenic obesity and diabetes was particularly pronounced among women and adults younger than 60 years. Guan noted that while excess body weight is widely recognized as a diabetes risk factor, the findings highlight that muscle health plays an equally important role in determining an individual’s risk. The authors concluded that evaluating both body fat and muscle health could improve the identification of people at high risk of developing type 2 diabetes. Senior author Professor Mario Siervo from Curtin University’s Faculty of Health Sciences said healthcare providers should consider assessing muscle health alongside body weight. He added that maintaining muscle strength through regular physical activity, resistance training, and healthy lifestyle habits may help reduce the growing burden of type 2 diabetes, particularly as obesity rates continue to rise and populations age. Source: PTI

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One Billion More People Now Exposed to Extreme Heat Stress Than in the 1970s, Study Finds

A new study has revealed that nearly one billion more people across the world are now experiencing at least one day of extreme heat stress every year compared to the 1970s, highlighting the growing intensity, frequency, and duration of dangerous heat conditions globally. The research, conducted by scientists from the European Centre for Medium-Range Weather Forecasts based in the U.K. and Germany, suggests that governments urgently need stronger heat-health action plans, early warning systems, urban cooling strategies, and improved climate risk assessments to better protect populations from rising heat-related threats. Heat stress refers to the overall heat burden placed on the human body and is determined by multiple environmental factors, including temperature, humidity, wind speed, and solar radiation. Researchers used the Universal Thermal Climate Index (UTCI), commonly described as a “feels-like” temperature, to evaluate how these combined factors impact human health. Published in the journal Nature Climate Change, the study examined global heat stress data spanning from 1950 to 2024 and found that both daytime and nighttime temperatures have significantly intensified since the 1970s. According to the researchers, during the 1970s nearly 55 percent of the world’s population experienced around 90 days of strong heat stress annually. In today’s climate, that figure has increased to 70 percent. Exposure to at least one day of extreme heat stress has also risen from 16 percent to 22 percent globally, translating into roughly one billion additional people being affected. The analysis further found that nighttime temperatures are rising faster than daytime temperatures. The 10 warmest nights recorded annually have been warming at an average rate of 0.32 degrees Celsius per decade, slightly higher than the 0.27 degrees Celsius increase observed during the 10 hottest daytime periods. Researchers also noted that extreme “feels-like” temperatures are becoming more frequent across every continent, with subtropical regions witnessing the sharpest rise in heat exposure. Areas including southern parts of North America, southern Europe, northern and southern Africa, as well as South America, are now facing up to 50 extra days every year of strong to extreme heat stress compared to conditions seen in the 1970s. The findings add to growing concerns over the accelerating impact of climate change and underline the urgent need for countries worldwide to develop stronger adaptation measures as extreme heat events become increasingly common. Source: PTI

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India Aims to Eliminate Sickle Cell Anaemia Before 2047, Says President Murmu

Droupadi Murmu has expressed confidence that India will eliminate sickle cell anaemia much before the government’s 2047 target, urging all states to intensify efforts and spread awareness about the disease, particularly among tribal communities where prevalence remains significantly higher. Speaking at a government event in Omkareshwar, Khandwa district of Madhya Pradesh, the President said that with collective participation from all states, the country is well-positioned to achieve its mission of eradicating sickle cell-related diseases ahead of schedule. She highlighted that since the launch of the National Sickle Cell Anaemia Elimination Mission in 2023, several major milestones have already been achieved, including the screening of over seven crore individuals aged between 0 and 40 years. The initiative has so far identified nearly 2.5 lakh affected patients and over 20 lakh carriers, making it one of the world’s largest genetic disease screening programmes. President Murmu also commended Madhya Pradesh for screening more than 1.25 crore people and distributing genetic counselling cards to a majority of beneficiaries. She emphasized that sickle cell anaemia should not be underestimated, as the hereditary disease passes from one generation to another, but can be treated and eventually eliminated through sustained intervention. The President praised the mission launched by Narendra Modi in Shahdol in 2023, describing it as India’s first nationwide campaign integrating public health, tribal welfare, genetic science, and digital monitoring. She noted that 17 states are actively participating in the campaign to help India achieve a sickle cell disease-free future. Source: The Hindu

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