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WHO Launches Biomanufacturing Workforce Training Initiative for Global Health Resilience

The World Health Organization (WHO) has unveiled the WHO Biomanufacturing Workforce Training Initiative in response to the COVID-19 pandemic’s impact on global supply chains, particularly affecting low- and middle-income countries’ access to essential medical products. This initiative aims to address the shortage of biomanufacturing capacity and qualified workforce in LMICs, which hinders the local production of biological products crucial for addressing global health challenges. Coordinated by the Local Production and Assistance (LPA) Unit of WHO, in collaboration with the WHO Academy and WHO Science Division, the initiative will provide accessible and tailored training programs aligned with international standards. Dr. Jicui Dong, Unit Head of the LPA Unit, will lead the initiative, focusing on three pillars: existing capacity-building activities within WHO, the Global Training Hub for Biomanufacturing (GTH-B), and regional training centers. WHO’s capacity-building programs have a track record of success in providing technical assistance to manufacturers and Member States. These programs include virtual and hands-on training sessions tailored to real-life scenarios, promoting sustainable and quality local production. The GTH-B, established in 2023 with the Republic of Korea, offers training programs on manufacturing best practices and vaccinology to LMICs, including hands-on training in manufacturing facilities. Regional training centers, as recommended by the 2nd World Local Production Forum, will further enhance geographical diversity and resource synchronization. Expressions of interest for regional training centers to join the global network under the Biomanufacturing Workforce Training Initiative will be invited soon. By enhancing bioproduction capabilities in LMICs, the WHO Biomanufacturing Workforce Training Initiative seeks to strengthen global health resilience and address disparities in access to essential medical products. This initiative underscores WHO’s commitment to promoting equitable solutions and building a skilled workforce to combat current and future health challenges.

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WHO Calls for Regulation of AI in Healthcare Due to Risks, Citing Bias and Privacy Concerns

News on Health

The World Health Organization (WHO) is calling for the regulation of artificial intelligence (AI) in healthcare due to the associated risks, according to a report. WHO emphasizes the need to establish safety and efficacy in AI tools, make them accessible to those who require them, and encourage communication among AI developers and users. While recognizing AI’s potential to enhance healthcare by strengthening clinical trials, improving diagnosis and treatment, and enhancing healthcare professionals’ knowledge and skills, the report by data and analytics company GlobalData highlights the rapid deployment of AI technologies without a full understanding of their long-term implications, which could pose risks to healthcare professionals and patients. Alexandra Murdoch, a Senior Analyst at GlobalData, acknowledges the significant benefits of AI in healthcare but also highlights the risks associated with rapid adoption. AI systems in healthcare often have access to personal and medical information, necessitating regulatory frameworks to ensure privacy and security. Other challenges with AI in healthcare include unethical data collection, cybersecurity vulnerabilities, and the reinforcement of biases and dissemination of misinformation. An example of AI biases is found in a Stanford University study, which revealed that some AI chatbots provided inaccurate medical information about people of color. In this study, nine questions were posed to four AI chatbots, including OpenAI’s ChatGPT and Google’s Bard, and all four chatbots provided inaccurate information related to race and kidney and lung function. The use of such false medical information is a cause for concern, as it could lead to issues like misdiagnoses and improper treatment for patients of color. WHO has identified six areas for regulating AI in healthcare, with a focus on managing the risks associated with AI amplifying biases in training data. These areas for regulation include transparency and documentation, risk management, data validation and clarity of AI’s intended use, a commitment to data quality, privacy and data protection, and the promotion of collaboration. Alexandra Murdoch hopes that by outlining these regulatory areas, governments and regulatory bodies can develop regulations to safeguard healthcare professionals and patients while fully harnessing the potential of AI in healthcare.

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India Leads Global Preterm Births in 2020, Lancet Study Reveals

In 2020, India witnessed the highest number of preterm births globally, with a staggering 3.02 million cases, constituting over 20 percent of all premature births worldwide, as revealed by a study published in The Lancet journal. This research, conducted by experts from the World Health Organization (WHO), the United Nations Children’s Fund (UNICEF), and the London School of Hygiene and Tropical Medicine, UK, further disclosed that more than half of all premature births in 2020 occurred in just eight countries. Following India, the countries with the highest preterm birth rates were Pakistan, Nigeria, China, Ethiopia, Bangladesh, the Democratic Republic of the Congo, and the United States, according to the researchers. The notable prevalence of preterm births in these regions is partly attributable to their substantial population sizes, high numbers of total births, and underdeveloped healthcare systems that struggle to provide high-quality family planning, antenatal care, and childbirth services to all those in need. Globally, approximately 13.4 million babies were born prematurely in 2020, with nearly one million succumbing to complications associated with preterm birth. This data equates to roughly one in ten babies being born prematurely, before completing 37 weeks of pregnancy worldwide. Given that prematurity ranks as the leading cause of child mortality in their early years, there is an urgent need to bolster both preterm infant care and preventative measures, particularly focusing on maternal health and nutrition to enhance child survival, emphasize the authors of the study. Furthermore, preterm birth significantly increases the likelihood of major illnesses, disabilities, developmental delays, and even chronic diseases like diabetes and heart conditions in adulthood for those who survive. This study derives its estimates from data that is representative of populations and national statistics, enabling internationally comparable assessments for the year 2020. It highlighted that India had the highest incidence of preterm births in 2020, totalling 3.02 million cases, accounting for over a fifth of all preterm births worldwide. While most high preterm birth rates were observed in low and middle-income nations, rates of 10 percent or higher were also evident in high-income countries such as Greece and the United States. Within South Asia, Bangladesh reported the highest preterm birth rate in 2020 at 16.2 percent, followed by Pakistan at 14.4 percent, and India at 13.0 percent. In Latin America, the rates ranged from 5.8 percent in Nicaragua to 12.8 percent in Suriname. As birth registration and facility-based deliveries have increased, data on the prevalence of preterm births has improved. Nevertheless, there are still 92 countries lacking sufficient nationally representative data. Consequently, the authors call for sustained efforts to enhance data availability, quality, and sharing to better target support and action where it is most needed. Dr. Anshu Banerjee, Director of Maternal, Newborn, Child, and Adolescent Health and Ageing at WHO, emphasized the vulnerability of preterm babies to life-threatening health complications and the necessity for dedicated care and attention. He stressed the urgency of substantial investments in services supporting preterm infants and their families, as well as a heightened focus on prevention, particularly ensuring access to quality healthcare before and during pregnancies. The researchers underscored that preterm birth is not exclusive to low and middle-income countries, as the data clearly reveals its impact on families worldwide, including some high-income countries such as Greece (11.6 percent) and the United States (10 percent).

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Polio Remains a Public Health Emergency of International Concern: WHO

The World Health Organization (WHO) has issued a report stating that the risk of the poliovirus spreading internationally remains a significant concern for public health. Currently, there are no travel restrictions in place for Pakistan. The potential for the international transmission of Wild Poliovirus type 1 (WPV1) in Pakistan, Afghanistan, and Africa is influenced by various factors. One of the reasons for polio transmission in Pakistan is the ongoing spread of the virus from eastern Afghanistan across the border. Additionally, there is a worrisome number of unvaccinated children in southern Afghanistan, posing a continuous risk of WPV1 reintroduction in that region. The report highlights suboptimal immunization coverage during vaccination campaigns in southeastern Africa, specifically in Malawi, Mozambique, Zambia, and Zimbabwe, which may lead to insufficient population immunity to stop transmission. In Pakistan, a new WPV1 case was reported in Khyber Pakhtunkhwa province on February 20, 2023. Furthermore, environmental surveillance has detected three positive samples in 2023, two in Punjab and one in KP, with two of them linked to viruses circulating in Afghanistan. In Afghanistan, no new cases have been reported in 2023, with the last case occurring on August 29, 2022. However, there have been 18 positive environmental samples in 2023, all from the eastern region, with three from Kunar and 15 from Nangarhar. Regarding the WPV1 outbreak in southern Africa, there have been no new cases reported since August 10, 2022, in Mozambique. To mitigate the risk of polio spread, the WHO committee recommends that all residents and long-term visitors (staying more than four weeks) of all ages should receive a dose of either bivalent oral poliovirus vaccine (bOPV) or inactivated poliovirus vaccine (IPV) between four weeks and 12 months before international travel. Travelers should also obtain an International Certificate of Vaccination or Prophylaxis as proof of vaccination. The committee emphasizes the need to restrict international travel for residents lacking appropriate polio vaccination documentation at the point of departure, regardless of the mode of transportation.

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