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Monday, April 13, 2026 4:21 AM

Nature Medicine

India Bears Second-Highest Global Economic Burden from Diabetes: Study

India is facing the world’s second-largest economic burden due to diabetes, estimated at USD 11.4 trillion, according to a new international study. The United States tops the list with costs of USD 16.5 trillion, followed by China at USD 11 trillion. The study, conducted by researchers from institutions including the International Institute for Applied Systems Analysis and the Vienna University of Economics and Business in Austria, assessed the economic impact of diabetes across 204 countries between 2020 and 2050. The findings have been published in the journal Nature Medicine. Globally, diabetes-related costs are estimated at nearly USD 10 trillion when excluding unpaid care provided by family members, accounting for about 0.2 per cent of the world’s annual GDP. However, when informal caregiving is included, the total economic burden surges to USD 152 trillion, or roughly 1.7 per cent of global GDP. Researchers noted that informal care alone contributes close to 90 per cent of the total economic burden, as people with diabetes live significantly longer with the condition than they face mortality risks. This extended care often forces family caregivers to reduce work hours or exit the labour market, adding to economic losses. In purchasing power terms, the study estimated diabetes-related costs at INT$ 1.6 trillion for India, INT$ 2.5 trillion for the United States, and INT$ 1.0 trillion for China. When losses from informal care are included, the figures rise sharply, with India’s burden reaching INT$ 11.4 trillion. For India and China, the high costs are largely driven by the sheer size of the diabetic population, while in the United States, higher treatment expenses and diversion of physical capital are the main contributors. The study also highlighted stark disparities between high- and low-income countries, noting that treatment costs form a much larger share of the burden in wealthier nations due to better access to medical care. The researchers stressed that diabetes poses a greater economic challenge globally than conditions such as cancer or Alzheimer’s disease. They emphasized that prevention through healthier lifestyles, including regular exercise and balanced diets, remains the most effective strategy to curb both health and economic impacts. Widespread screening, early diagnosis, and timely treatment were also identified as critical measures. According to earlier research published in The Lancet in November 2024, more than a quarter of the world’s diabetic population currently lives in India. Source: PTI

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Breakthrough in Understanding Childhood Immunity to Strep A Could Accelerate Vaccine Development

A team of scientists has uncovered how young children naturally build immunity against Group A Streptococcus (Strep A), a bacterial infection responsible for up to half a million deaths worldwide each year. The finding could significantly speed up the creation of a life-saving vaccine. Strep A is a common bacterium that can cause mild illnesses like sore throat and skin infections, but in severe cases, it can trigger life-threatening diseases. While deaths from Strep A are rare in wealthier nations, outbreaks can be devastating. In late 2022, a surge in cases across the UK and Europe claimed hundreds of lives, including those of many children. The burden is far greater in low- and middle-income countries, where thousands die annually from the infection. Researchers from the University of Sheffield, working with the Medical Research Council (MRC) Unit The Gambia at the London School of Hygiene and Tropical Medicine, tracked how Gambian children acquire natural immunity. Published in Nature Medicine, the study identified specific antibodies linked to protection from Strep A, marking a crucial step toward vaccine design. The team observed that babies are born with some immunity passed down from their mothers, but this protection fades quickly. Young children, however, develop robust antibody responses to different components of the bacteria after repeated exposure. This discovery pinpoints a key window for immune development, which could guide more effective vaccination strategies. Lead researcher Dr. Alex Keeley said this is the first time scientists have seen in humans how antibodies generated through vaccination might prevent Strep A infections. Gambian scientist Fatouamta Camara described the infection’s “devastating burden” on communities and expressed hope that a vaccine could break the cycle of illness and socio-economic hardship. The research was a collaboration between Sheffield’s Florey Institute of Infection and the GSK Vaccine Institute for Global Health. Professor Thushan de Silva, who co-directed the study, emphasised the importance of cross-institutional efforts in delivering impactful global health research. Source: PTI

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India May Face Over 1.6 Million Gastric Cancer Cases, Global Study Warns

A new international study published in Nature Medicine has sounded the alarm over a possible surge in gastric cancer cases, predicting that more than 15 million individuals born between 2008 and 2017 could develop the disease globally during their lifetime. India is projected to bear a significant burden, second only to China, with an estimated 1.6 million cases if current prevention efforts remain unchanged. The research, led by the International Agency for Research on Cancer (IARC), the cancer research wing of the World Health Organization, used global cancer incidence data from GLOBOCAN 2022 along with UN demographic forecasts. It found that nearly two-thirds of future gastric cancer cases will likely emerge in Asia, with India and China alone expected to contribute about 6.5 million new diagnoses. A key finding of the study highlights that 76% of these cases could be linked to Helicobacter pylori—a widespread and chronic bacterial infection of the stomach that significantly increases cancer risk. Despite being preventable and treatable, H. pylori remains a major health challenge in many countries. Gastric cancer is currently the fifth most deadly cancer worldwide. The study also points to an anticipated six-fold rise in cases across sub-Saharan Africa, where the current incidence is relatively low. Experts behind the research are urging governments to invest in large-scale preventive measures—especially in screening and treatment programs targeting H. pylori. They stress that such interventions could slash future cancer cases by as much as 75%. The researchers warn that an ageing global population, along with rising cancer rates in younger people, could undo recent progress in cancer control if swift action is not taken. The findings reinforce the urgent need for countries, particularly in Asia, to enhance public health strategies focusing on early diagnosis, education, and bacterial eradication to curb the looming threat of gastric cancer. Source: CNBCTV18

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